Phenolic Compounds from the Lichen Lobaria orientalis
| Autor: | Warinthorn Chavasiri, Jacques Mortier, Phung P. K. Nguyen, Dung M. T. Nguyen, Lien M. T. Do, Vy T. Nguyen |
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| Rok vydání: | 2017 |
| Předmět: |
Circular dichroism
Lichens Stereochemistry Pharmaceutical Science Depsides 01 natural sciences Analytical Chemistry Stereocenter Lactones chemistry.chemical_compound Ascomycota Phenols Drug Discovery Lichen Pharmacology Molecular Structure 010405 organic chemistry Circular Dichroism Phenyl Ethers Organic Chemistry Acetal Absolute configuration Resorcinols 0104 chemical sciences 010404 medicinal & biomolecular chemistry Vietnam Complementary and alternative medicine chemistry Molecular Medicine Lobaria orientalis |
| Zdroj: | Journal of Natural Products. 80:261-268 |
| ISSN: | 1520-6025 0163-3864 |
| Popis: | The chemical investigation of the EtOAc extract of Lobaria orientalis collected in the southwestern part of Central Vietnam led to the isolation of new β-orcinol depsidones, lobarientalones A and B (1 and 2), and diphenyl ethers, lobariethers A-E (3-7). These types of structures are often reported in different lichen species, but the absolute configuration of the stereogenic acetal center has not been defined. This is the first assessment of the (1S) absolute configuration of the stereogenic acetal center using electronic circular dichroism (ECD) spectroscopic data and by comparison with the ECD data of analogous compounds. Based on the co-occurrence of the depsidones, 1,10-di-O-methylstictic acid (8) and (1-2), and diphenyl ethers (3-7), a plausible biosynthesis route toward 1-8 is proposed. |
| Databáze: | OpenAIRE |
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