Effects of acute physical exercise in the light phase of sleep in rats with temporal lobe epilepsy
| Autor: | Cristiano de Lima, Tathiana A. Alvarenga, Monica L. Andersen, Sergio Tufik, Rodrigo Luiz Vancini, Ricardo Mario Arida, Daniel Ninello Polesel, Gabriela Matos |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Male
0301 basic medicine Physical exercise Motor Activity Temporal lobe Random Allocation 03 medical and health sciences Epilepsy 0302 clinical medicine medicine Animals Rats Wistar Treadmill Electrocorticography Slow-wave sleep medicine.diagnostic_test Pilocarpine Brain medicine.disease Sleep in non-human animals Electrodes Implanted Exercise Therapy Disease Models Animal 030104 developmental biology Epilepsy Temporal Lobe Neurology Anesthesia Wakefulness Neurology (clinical) Sleep Psychology 030217 neurology & neurosurgery |
| Zdroj: | Epilepsy Research. 136:54-61 |
| ISSN: | 0920-1211 |
| DOI: | 10.1016/j.eplepsyres.2017.07.012 |
| Popis: | Objective Our aim was to investigate the influence of an acute exercise session on sleep pattern in rats with temporal lobe epilepsy (TLE). Methods Twenty male Wistar rats were randomly assigned to 4 groups: control (C); acute exercise (EX); epilepsy (E) and epilepsy acute exercise (EEX). Two sleep electrocorticography recordings were performed during the light phase [baseline and day 2 (after the acute physical exercise session)]. After baseline recording, the exercise groups (EX and EEX) were submitted to an exercise session on a motor-driven treadmill at 12 m/min for 30 min. Twelve hours later, the rats were submitted to the second sleep recording. Results At baseline, the E group showed a higher wakefulness and a lower Total sleep time, Slow Wave Sleep and REM sleep compared with the C group. After acute exercise, there was an increase in Total sleep time and Slow Wave Sleep and a decrease of wakefulness in EEX (+11.10%, +20.29% and −11.25%, respectively) and EX (+5.20%, +11.60% and −8.12%, respectively) groups. Conclusion These findings suggest that acute physical exercise positively impacts the sleep pattern of rats with TLE, inducing a more consolidated sleep. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect