Cold sensitivity and associated factors: a nested case–control study performed in Northern Sweden
| Autor: | Jens Wahlström, Hans Pettersson, Albin Stjernbrandt, Ingrid Liljelind, Daniel Carlsson, Tohr Nilsson |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
Raynaud’s phenomenon medicine.medical_treatment cold exposure frostbite 0302 clinical medicine Peripheral Nerve Injuries Surveys and Questionnaires cold sensitivity Medicine 030212 general & internal medicine Young adult 030222 orthopedics Rehabilitation Frostbite Environmental exposure Middle Aged Cold Temperature Original Article Female medicine.symptom Adult Adolescent Migraine Disorders Cold exposure 03 medical and health sciences Arbetsmedicin och miljömedicin Young Adult Environmental health Rheumatic Diseases Humans Obesity Vascular Diseases Cold Injury Aged Sweden business.industry Public Health Environmental and Occupational Health Case-control study Occupational Health and Environmental Health Environmental Exposure Anthropometry medicine.disease Hand Cold sensitivity Logistic Models Case-Control Studies Nested case-control study Somatosensory Disorders hand business |
| Zdroj: | International Archives of Occupational and Environmental Health |
| ISSN: | 1432-1246 0340-0131 |
| Popis: | Aim To identify possible risk factors for cold sensitivity, by comparing cases to controls with regard to demographic and anthropometric characteristics, previous illnesses and injuries as well as ambient exposures. Methods Through a questionnaire responded to by the general population (n=12,627) cold sensitivity cases (n=502) and matched controls (n=1,004) were identified and asked to respond to a second questionnaire with focus on different aspects of cold sensitivity, hereditary factors, previous diseases, medication, tobacco use as well as exposure to ambient cold climate and hand-arm vibration (HAV). Results In total, 997 out of 1506 study subjects answered the second questionnaire, 374 cases and 623 match controls. Identified risk factors among the cases were frostbite of the hands Odds Ratio (OR) 10.3 (95% confidence interval (CI) 5.5-19.3), rheumatic disease OR 3.1 (95% CI 1.7-5.7), upper extremity nerve injury OR 2.0 (95% CI 1.3-3.0), and vascular disease OR 1.9 (95% CI 1.2-2.9). Sex differences in risk factors were HAV exposure for men and cold exposure for women increased the risk of cold sensitivity. Rheumatic diseases and migraine increased the risk of cold sensitivity among women but not among men. Conclusions The present study shows that cold sensitivity is associated with both inherent factors, acquired conditions and external exposures. Among acquired conditions, frostbite, vascular disease, nerve injury, joint disorders and migraine are significantly related to the reporting of cold sensitivity. Among external exposures, both cold climate and HAV exposure are significantly associated to cold sensitivity, and thus suitable targets for primary preventive measures. There was a difference in risk factors related to sex. HAV exposure for men and cold exposure for women increased the risk of cold sensitivity. Originally included in thesis in manuscript form with title [Cold sensitivity and associated factors: a case-control study performed in northern Sweden] CHINS |
| Databáze: | OpenAIRE |
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