Burden of testicular, paratesticular and extragonadal germ cell tumours in Europe

Autor: Rafael Marcos-Gragera, Eva Ardanaz, Magdalena Bielska-Lasota, Stanislaw Gozdz, Marina Vercelli, Pascale Grosclaude, Jan Adolfsson, Michel Coleman, Lucia Mangone, Andrea Necchi, MARIA JOSE SANCHEZ-PEREZ, Juan Melchor, Michael Schaapveld, Nicola Nicolai, Diego Serraino, Giske Ursin, Maria Zwierko, Jan Willem Coebergh, Emanuele Crocetti, Roberta De Angelis, Stefano Ferretti, Andrea Tavilla, Jourik Gietema, Gemma Gatta, ANGELO DEI TOS, Fabio Falcini, Andrés Cervantes, Riccardo A. Audisio, Paolo Contiero, Rosario Tumino, Laufey Tryggvadottir, Jadwiga Rachtan, Franco Berrino, Alessandro Gronchi, Trama Annalisa
Přispěvatelé: Usel, Massimo, Damage and Repair in Cancer Development and Cancer Treatment (DARE), Guided Treatment in Optimal Selected Cancer Patients (GUTS), Trama, A, Mallone, S, Nicolai, N, Necchi, A, Schaapveld, M, Gietema, J, Znaor, A, Ardanaz, E, Berrino, F
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Male
Cancer Research
Survival
Rare Diseases/epidemiology/mortality
rare cancers
SPERMATOCYTIC SEMINOMA
PROGNOSTIC-FACTORS
Cost of Illness
Prevalence
Cancer registries
Registries
Young adult
RARE CANCER
Child
paratesticular and extragonadal germ cell tumours
Relative survival
Incidence (epidemiology)
Incidence
Middle Aged
Neoplasms
Germ Cell and Embryonal
Neoplasms
Germ Cell and Embryonal/epidemiology/mortality
Rare diseases
PREVALENCE
Europe
medicine.anatomical_structure
Oncology
OF-THE-LITERATURE
Child
Preschool
Sex cord tumour
Spermatocytic seminoma
Female
testicular
Germ cell
Adult
medicine.medical_specialty
Extragonadal
Adolescent
Urology
paratesticular
Testicular Neoplasms/epidemiology/mortality
CLASSIFICATION
Europe/epidemiology
NO
Young Adult
Age Distribution
Testicular Neoplasms
Testicular cancer
medicine
Humans
Survival analysis
ddc:613
Gynecology
extragonadal germ cell tumours
Germ cell tumour
business.industry
Paratesticular cancer
MORTALITY
Cancer
Infant
Testicular
medicine.disease
Rare diseases
Testicular cancer
Paratesticular cancer
Germ cell tumour
Sex cord tumour
Cancer registries
Incidence
Prevalence
Survival
Survival Analysis
TRENDS
CANCER INCIDENCE
Cancer research
business
Zdroj: European Journal of Cancer, Vol. 48, No 2 (2012) pp. 159-69
European Journal of Cancer, 48(2), 159-169. ELSEVIER SCI LTD
ISSN: 0959-8049
Popis: We provide updated estimates of survival, incidence, complete prevalence, and proportion cured for patients with testicular/paratesticular and extragonadal germ cell cancers in Europe, grouped according to the new list of cancer types developed by RARECARE. We collected data, archived in European cancer registries, with vital status information available to 31st December 2003.We analysed 26,000 cases of testicular, paratesticular and extragonadal germ cell cancers diagnosed 1995-2002, estimating that about 15,600 new testicular/paratesticular and 630 new extragonadal cancer cases occurred per year in EU27, with annual incidence rates of 31.5/1,000,000 and 1.27/1,000,000, respectively. Slightly more than 436,000 persons were alive at the beginning of 2008 with a diagnosis of testicular/paratesticular cancer, and about 17,000 with a diagnosis of extragonadal germ cell cancer.Five-year relative survival was 96% for testicular/paratesticular cancer and 71% for extragonadal germ cell cancer; the proportions cured were 95% and 69%, respectively. We found limited variation in survival between European regions except for non-semino matous testicular cancer, for which five-year relative survival ranged from 86% in Eastern Europe to 96% in Northern Europe. Survival for all cancer types considered decreased with increasing age at diagnosis.Further investigation is required to establish the real reasons for the lower survival in Eastern Europe. Considering the high prevalence of these highly curable cancers, it is important to monitor patients long-term, so as to quantify treatment-related risks and develop treatments having limited impact on quality of life. (C) 2011 Elsevier Ltd. All rights reserved.
Databáze: OpenAIRE
Externí odkaz: