Impact of intermittent fasting on laboratory, radiological, and anthropometric parameters in NAFLD patients

Autor: Hanaa Badran, Maha Elsabaawy, Ahmed Sakr, Mahmoud Eltahawy, Mahitab Elsayed, Dalia Elsabaawy, Mervat Abdelkreem
Rok vydání: 2022
Předmět:
Zdroj: Clinical and experimental hepatology. 8(2)
ISSN: 2392-1099
Popis: Despite the ample flow of non-alcoholic fatty liver disease (NAFLD) drugs in the pipeline, lifestyle modifications are still the optimal solution of NAFLD. The aim of the study was to assess short term effects of Ramadan fasting (RF) as a sort of intermittent fasting (IF) on biochemical, radiological, and anthropometric parameters of NAFLD patients.Ninety-eight NAFLD patients were recruited and voluntarily subjected to 16 hours daily fasting for an average of 22-29 days, without special dietary recommendations. Anthropometric, laboratory and radiological parameters were measured before, at 30 days, and one month after fasting (fasting and non-fasting phases).Patients were mostly rural (76%), hypertensive (34.7%), diabetic (43.9%), and female (76.8%), with overt criteria of metabolic syndrome (67.3%). Liver transaminases (ALT and AST) were ameliorated significantly after fasting (Intermittent fasting led to momentous improvements in ultrasonographic, biochemical, and anthropometric parameters of NAFLD especially in early phases and prediabetics.
Databáze: OpenAIRE