Quantitative analysis of repaired rabbit supraspinatus tendons (± channeling) using magnetic resonance imaging at 7 Tesla
| Autor: | Adnan Sheikh, Guy Trudel, Hakim Louati, Gerd Melkus, Justin Thomas, Samuel Duchesne-Bélanger, Greg O. Cron, Mark E. Schweitzer, Peder E. Z. Larson, Odette Laneuville |
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| Rok vydání: | 2021 |
| Předmět: |
Materials science
Adult female medicine.diagnostic_test Relaxation (NMR) Magnetic resonance imaging musculoskeletal system Supraspinatus tendon Sagittal plane Tendon Fat saturation medicine.anatomical_structure medicine Original Article Radiology Nuclear Medicine and imaging Rotator cuff Biomedical engineering |
| Zdroj: | Quant Imaging Med Surg |
| ISSN: | 2223-4306 2223-4292 |
| DOI: | 10.21037/qims-20-1343 |
| Popis: | BACKGROUND: The quantitative assessment of supraspinatus tendons by conventional magnetic resonance is limited by low contrast-to-noise ratio (CNR). Magnetic resonance imaging (MRI) scanners operating at 7 Tesla offer high signal-to noise ratio (SNR), low CNR and high spatial resolution that are well-suited for rapidly relaxing tissues like tendons. Few studies have applied T2 and T2* mapping to musculoskeletal imaging and to the rotator cuff tendons. Our objective was to analyze the T2 and T2* relaxation times from surgically repaired supraspinatus tendons and the effect of bone channeling. METHODS: One supraspinatus tendon of 112 adult female New Zealand white rabbits was surgically detached and repaired one week later. Rabbits were randomly assigned to channeling (n=64) or control (n=48) groups and harvested at 0, 1, 2, and 4 weeks. A 7T magnet was used for signal acquisition. For T2 mapping, a sagittal multi slice 2D multi-echo spin-echo (MESE) CPMG sequence with fat saturation was applied and T2* mapping was performed using a 3D UTE sequence. Magnetic resonance images from supraspinatus tendons were analyzed by two raters. Three regions of interest were manually drawn on the first T2-weighted dataset. For T2 and T2*, different ROI masks were generated to obtain relaxation times. RESULTS: T2-weighted maps but not T2*-weighted maps generated reliable signals for relaxation time measurement. Torn supraspinatus tendons had lower T2 than controls at the time of repair (20.0±3.4 vs. 25.6±3.9 ms; P0.05). CONCLUSIONS: Supraspinatus tendons detached for 1 week had shorter T2 relaxation time compared to contralateral as measured with 7T MRI. |
| Databáze: | OpenAIRE |
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