Left extended hepatectomy for a metastatic gastrointestinal stromal tumor after a disease-free interval of 17 years: report of a case
| Autor: | Lea Matsuoka, Maria Stapfer, Rod Mateo, Nicolas Jabbour, Win Naing, Singh Gagandeep, Rick Selby |
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| Rok vydání: | 2006 |
| Předmět: |
Oncology
medicine.medical_specialty Stromal cell Time Factors Gastrointestinal Stromal Tumors medicine.medical_treatment Complete resection Metastasis Surgical oncology Internal medicine medicine Hepatectomy Humans Retroperitoneal Neoplasms Stromal tumor neoplasms Disease free interval GiST Jejunal Neoplasms business.industry Liver Neoplasms General Medicine Middle Aged medicine.disease digestive system diseases Surgery Female Radiology business |
| Zdroj: | Surgery today. 37(1) |
| ISSN: | 0941-1291 |
| Popis: | Gastrointestinal stromal tumors (GISTs), although rare, are frequently diagnosed with liver metastasis. These metastatic GISTs are poorly responsive to conventional chemotherapy; however, recent studies report improved survival after complete surgical resection of liver metastases. On the other hand, few reports describe the treatment of delayed liver metastasis after resection of a primary GIST. We report the case of a 55-year-old woman found to have liver metastasis from a GIST after a 17-year disease-free interval. The patient underwent a left extended hepatectomy for a complete resection of the metastatic GIST and is alive and well 30 months later. To our knowledge, this is the longest disease-free interval reported in the literature, and emphasizes the importance of considering late metastasis when evaluating patients with a history of GIST. Thus, surgical resection of delayed liver metastasis from a GIST should be considered as primary therapy. |
| Databáze: | OpenAIRE |
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