Canthaxanthin retinopathy. Anatomic and functional reversibility
| Autor: | Alain P. Rousseau, Carmen Harnois, Mario Malenfant, Jacques Samson |
|---|---|
| Rok vydání: | 1989 |
| Předmět: |
Adult
medicine.medical_specialty Canthaxanthin Light Fundus Oculi Eye disease Observation period Retina chemistry.chemical_compound Retinal Diseases Ophthalmology medicine Humans RETINAL DEPOSITS business.industry Significant difference Middle Aged medicine.disease Carotenoids Surgery medicine.anatomical_structure chemistry Sensory Thresholds business Crystallization Retinopathy |
| Zdroj: | Archives of ophthalmology (Chicago, Ill. : 1960). 107(4) |
| ISSN: | 0003-9950 |
| Popis: | • Canthaxanthin intake is associated with golden yellow crystalline deposits in the retina around the macula and low static luminance threshold. Our study assesses the anatomic and functional reversibility of canthaxanthin retinopathy. The number of retinal deposits was evaluated in nine patients, two to four times over a mean period of 55 months. There was no significant difference after a nine-month follow-up. A statistically significant decrease in the number of retinal deposits was found after an observation period of 26 months. The deposits disappeared slowly, while some remained even seven years after canthaxanthin therapy was discontinued. Threshold static perimetry performed on eight patients with retinopathy and seven controls did not differ significantly between the two groups at the end of the follow-up period. The results demonstrate that canthaxanthin retinopathy is reversible. |
| Databáze: | OpenAIRE |
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