Effectiveness of an exercise programme on physical function in patients discharged from hospital following critical illness: a randomised controlled trial (the REVIVE trial)
| Autor: | John McCaffrey, Kathryn McDowell, T John Trinder, Paul Johnston, Chris Clarke, Judy Bradley, Evie Gardner, Gavin Lavery, Sally Murphy, Daniel F. McAuley, Brenda O'Neill, Brian Mullan, Bronagh Blackwood, Michaeline Kelly |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine medicine.medical_specialty Time Factors Critical Illness medicine.medical_treatment Walk Test Physical function law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law Surveys and Questionnaires Intervention (counseling) Humans Medicine Single-Blind Method In patient Pulmonary rehabilitation Prospective Studies 030212 general & internal medicine Exercise Aged Rehabilitation business.industry 030208 emergency & critical care medicine Middle Aged Patient Discharge Self Efficacy Exercise Therapy Exercise programme Critical illness Physical therapy Female business Follow-Up Studies |
| Zdroj: | McDowell, K, O'Neill, B, Blackwood, B, Clarke, C, Gardner, E, Johnston, P, Kelly, M, McCaffrey, J, Mullan, B, Murphy, S, Trinder, T J, Lavery, G, McAuley, D F & Bradley, J 2016, ' Effectiveness of an exercise programme on physical function in patients discharged from hospital following critical illness: a randomised controlled trial (The REVIVE trial) ', Thorax, vol. 72 . https://doi.org/10.1136/thoraxjnl-2016-208723 |
| ISSN: | 1468-3296 0040-6376 |
| Popis: | Objective To investigate the effectiveness of a 6-week exercise programme in patients discharged home following critical illness compared with standard care.Design Multicentre prospective phase II randomised controlled trial, with blinded outcome assessment after hospital discharge, following the 6-week intervention and at 6 months.Participants 60 patients (30 per group) aged ≥18 years, mechanically ventilated >96 hours, and not in other rehabilitation, that is, cardiac or pulmonary rehabilitation programmes. Participants in the intervention group completed an individually tailored (personalised) exercise programme.Outcome measures Primary outcome measure was SF-36 physical functioning following the intervention. Secondary outcomes included a range of performance-based and patient-reported measures.Results Improvements in the primary outcome did not differ significantly between groups (mean difference (95% CI) 3.0 (−2.2 to 8.2), p=0.26). The intervention group showed significant improvement compared with the control group (mean difference (95% CI)) in SF-36 role physical (6.6 (0.73 to 12.5), p=0.03); incremental shuttle walk test (83.1 m (8.3 to 157.9), p=0.03); functional limitations profile (−4.8 (−8.7 to −0.9), p=0.02); self-efficacy to exercise (2.2 (0.8 to 3.7), p=0.01) and readiness to exercise (1.3 (0.8 to 1.9), pConclusions There was no statistically significant difference in the primary outcome measure of self-reported physical function following this 6-week exercise programme. Secondary outcome results will help inform future studies.Trial registration number NCT01463579. (results), https://clinicaltrials.gov/ |
| Databáze: | OpenAIRE |
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