Sanger sequencing versus INNO-LiPA® HBV PreCore assay for routine detection of precore and basal core promoter mutations in hepatitis virus B chronically infected patients

Autor:	V. Pigot, Didier Hober, C. Hallaert, V. Canva, Enagnon Kazali Alidjinou, Laurence Bocket, Valérie Lambert
Rok vydání:	2018
Předmět:	Adult Male Microbiology (medical) Hepatitis B virus Adolescent Genotyping Techniques Inno lipa Biology medicine.disease_cause Young Adult 03 medical and health sciences Basal (phylogenetics) symbols.namesake Hepatitis B Chronic 0302 clinical medicine medicine Humans Promoter Regions Genetic Aged Sanger sequencing Hepatitis virus Promoter General Medicine Middle Aged Hepatitis B Core Antigens Virology Infectious Diseases 030220 oncology & carcinogenesis Mutation symbols Female 030211 gastroenterology & hepatology
Zdroj:	Diagnostic Microbiology and Infectious Disease. 90:277-279
ISSN:	0732-8893
Popis:	We compared the Sanger sequencing and the commercial INNO-LiPA® HBV assay for the routine detection of precore (PC) and basal core promoter (BCP) mutations of hepatitis B virus in chronically infected patients. The overall agreement rate between assays was 94.2% and 98.8% for the detection of PC and BCP mutations, respectively.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bd0f6b4bb53d1af7e864c9877078c6e https://doi.org/10.1016/j.diagmicrobio.2017.12.006 Zobrazit plný text záznamu Full Text from ScienceDirect