Histopathological and Bacteriological Analysis of Thrombus Material Extracted During Mechanical Thrombectomy in Acute Stroke Patients
| Autor: | María José Pedrosa-Jiménez, Óscar Ayo-Martín, Enrique Juliá-Molla, Laura Rojas-Bartolomé, Gemma Serrano-Heras, Francisco Hernández-Fernández, Tomás Segura, Juan David Molina-Nuevo, Rosa Angélica Barbella-Aponte, Jorge García-García |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Urinary system medicine.medical_treatment 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Medicine Humans Radiology Nuclear Medicine and imaging Prospective Studies Thrombus Stroke Septic embolism Aged Retrospective Studies Thrombectomy Endocarditis business.industry Incidence (epidemiology) Ultrasound Stent Thrombosis medicine.disease Surgery Treatment Outcome Infective endocarditis Female Cardiology and Cardiovascular Medicine business 030217 neurology & neurosurgery |
| Zdroj: | Cardiovascular and interventional radiology. 40(12) |
| ISSN: | 1432-086X |
| Popis: | Management of stroke secondary to septic emboli (SE) remains challenging, due to both the lack of specific recommendations and the gravity of the underlying pathology.The aim of this study is to describe the presence of SE in a series of mechanical thrombectomies (MT), analyzing technical complexity and outcomes with respect to the patients by means of histological analysis and microbiological study of the clot. All the retrieved clots were studied under an established protocol, including histopathological and bacteriological study with hematoxylin–eosin, Gram and Gomori trichrome staining.Technical complexity in SE with respect to the series was evaluated by analyzing time of the procedures, number of passes and use of intracranial definitive stents. Over a 24-month period, bacteria were detected in the retrieved clot of four out of 65 patients (incidence 6.2%). Two cases were eventually diagnosed with infective endocarditis, while the remaining two were diagnosed with urinary tract infection and respiratory septicemia, respectively. Three of the four patients (75%) required an intracranial definitive stent in order to achieve successful recanalization.These procedures were significantly longer (137.7 vs. 59.8 min, p |
| Databáze: | OpenAIRE |
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