Gigapixel confocal imaging using a massively parallel optical probe array with single directional infinite scanning
| Autor: | Nahyun Won, Ryung Shin, Runjia Han, Kyung-Jin Lee, Taekyung Kim, Woojae Choi, Dong-Hyun Kim, Shinill Kang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
lcsh:Medicine
02 engineering and technology Micro-optics 01 natural sciences Article law.invention 010309 optics Optics Confocal imaging law 0103 physical sciences lcsh:Science Massively parallel Physics Microlens Multidisciplinary Relay lens Pixel business.industry lcsh:R Imaging and sensing 021001 nanoscience & nanotechnology Lens (optics) Probe array lcsh:Q 0210 nano-technology business Parallelogram |
| Zdroj: | Scientific Reports Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020) |
| ISSN: | 2045-2322 |
| Popis: | Here we demonstrate high-throughput gigapixel confocal imaging using a massively parallel optical probe array with single directional infinite scanning. For implementation of the single directional infinite scan with high lateral resolution, a parallelogram array micro-objective lens module, composed of two wafer-level microlens arrays, is proposed to generate a massively parallel optical probe array for integration into the confocal imaging system, including an objective-side telecentric relay lens with a low-magnification. To test the feasibility of the proposed system with single directional infinite scanning, we designed and constructed a confocal imaging system using a parallelogram array of multi-optical probes with a massively parallel array size of 200 × 140. The constructed system provides a full width-half maximum lateral resolution of 1.55 μm, as measured by the knife-edge detection method, and a field-of-view width of 28.0 mm with a sampling interval of 1 μm/pixel. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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