Impact of preemptive hospitalization on health outcomes at the temporary COVID-19 hospital in Mexico City: a prospective observational study
| Autor: | Héctor Herrera Bello, Adrian Palacios Chavarria, Santiago Treviño Berlanga, Reyna Albertina Rosas Loza, Luis Alberto Martinez-Juarez, Rodrigo Ville Benavides, Julieta Lomelin-Gascon, Rodrigo Saucedo-Martínez, Alejandra Montoya, Lidia Moreno Castañeda, Luis Esteban Ramirez Gonzalez, Linda Morales Juárez, Mónica Arboleya Avendaño, Alonso Gutiérrez Romero, Ailyn Cendejas Schotman, Laura María Badel Ramos, Pablo Escalera Castillo, Andrea Gonzalez Rodriguez, Renate Victoria Álvarez Wyssmann, María Dolores Niembro Ortega, Roberto Tapia-Conyer, Rafael Ricardo Valdez Vazquez, Héctor Gallardo-Rincón, Liudmila Villegas Acosta, Erika Salinas Lezama, Jennifer Bertin Montoya |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
2019-20 coronavirus outbreak Coronavirus disease 2019 (COVID-19) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Infectious and parasitic diseases RC109-216 Health outcomes HFNC preemptive hospitalization Mexico city Pandemic medicine Pharmacology (medical) Mexico Original Research SARS-CoV-2 business.industry COVID-19 IMV pulse oximetry Infectious Diseases Emergency medicine Observational study temporary hospital CALL score business |
| Zdroj: | Therapeutic Advances in Infectious Disease, Vol 8 (2021) Therapeutic Advances in Infectious Disease |
| ISSN: | 2049-9361 |
| Popis: | Introduction:In response to the evolution of the coronavirus disease 2019 (COVID-19) pandemic, the admission protocol for the temporary COVID-19 hospital in Mexico City has been updated to hospitalize patients preemptively with an oxygen saturation (SpO2) of >90%.Methods:This prospective, observational, single-center study compared the progression and outcomes of patients who were preemptively hospitalized versus those who were hospitalized based on an SpO2⩽90%. We recorded patient demographics, clinical characteristics, COVID-19 symptoms, and oxygen requirement at admission. We calculated the risk of disease progression and the benefit of preemptive hospitalization, stratified by CALL Score: age, lymphocyte count, and lactate dehydrogenase (Results:Preemptive hospitalization significantly reduced the requirement for oxygen therapy (odds ratio 0.45, 95% confidence interval 0.31–0.66), admission to the intensive care unit (ICU) (0.37, 0.23–0.60), requirement for invasive mechanical ventilation (IMV) (0.40, 0.25–0.64), and mortality (0.22, 0.10–0.50). Stratification by CALL score at admission showed that the benefit of preemptive hospitalization remained significant for patients requiring oxygen therapy (0.51, 0.31–0.83), admission to the ICU (0.48, 0.27–0.86), and IMV (0.51, 0.28–0.92). Mortality risk remained significantly reduced (0.19, 0.07–0.48).Conclusion:Preemptive hospitalization reduced the rate of disease progression and may be beneficial for improving COVID-19 patient outcomes. |
| Databáze: | OpenAIRE |
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