Precursor effects on the physical, biological, and catalytic properties of Fagonia indica Burm.f. mediated zinc oxide nanoparticles
| Autor: | Malik Maaza, Lubna Rahman, Ikram Ullah, Zabta Khan Shinwari, Javed Iqbal, Safia Hameed, Ali Talha Khalil, Saleh Khamlich, Muhammad Numan, Banzeer Ahsan Abbasi, Fawaz Alasmari, Muhammad Ali |
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| Rok vydání: | 2021 |
| Předmět: |
Thermogravimetric analysis
Histology Plant Extracts Chemistry technology industry and agriculture Nanoparticle chemistry.chemical_element Zinc Antioxidants Medical Laboratory Technology chemistry.chemical_compound Spectroscopy Fourier Transform Infrared Zeta potential Nanoparticles Chelation Crystal violet Zinc Oxide Anatomy Fourier transform infrared spectroscopy Instrumentation health care economics and organizations Scherrer equation Nuclear chemistry |
| Zdroj: | Microscopy Research and Technique. 84:3087-3103 |
| ISSN: | 1097-0029 1059-910X |
| Popis: | We report a facile, green and precursor-based comparative study on the biosynthesis of zinc oxide (ZnO) nanoparticles (NPs) using anticancerous Fagonia indica as effective chelating agent. Biosynthesis was carried out using zinc sulfate and zinc acetate as precursor salts to make ZnOS and ZnOA NPs under similar experimental conditions which were characterized extensively for physical and biological properties. Scherrer equation deduced a mean crystallite size of ~23.4 nm for ZnOA NPs and ~41 nm for ZnOS NPs. The nature of the NPs was compared using UV, diffuse reflectance spectra, Fourier transform infrared spectroscopy, thermogravimetric analysis-DTA, selected area electron diffraction, EDS, zeta potential, high resolution (HR)-SEM, and HR-TEM. Detailed in vitro pharmacognostic activities revealed a significant therapeutic potential for ZnOA and ZnOS . Potential antimicrobial activities for the NPs and their nanocosmeceutical formulations are reported. ZnOA NPs were more cytotoxic to Leishmania tropica as compared to ZnOS . Significant antioxidant and protein kinase inhibition was obtained. The hemolytic assay indicated a hemocompatible nature of both ZnOA and ZnOS NPs. Catalytic degradation of crystal violet dye (CVD) by NPs was examined under different parameters (light, dark, UV). Furthermore, sonophotocatalytic degradation of CVD was also studied. Our results suggested that precursor can have a significant effect on the physical, biological, and catalytic properties of the NPs. In future, we recommend different other in vitro, in vivo biological activities, and mechanistic studies of these as-synthesized NPs. |
| Databáze: | OpenAIRE |
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