Epidemiology of adult atopic dermatitis
Autor: | Ryan Sacotte, Jonathan I. Silverberg |
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Rok vydání: | 2018 |
Předmět: |
Adult
0301 basic medicine medicine.medical_specialty Internationality Dermatology Disease Dermatitis Atopic Young Adult 030207 dermatology & venereal diseases 03 medical and health sciences Indirect costs Sex Factors 0302 clinical medicine Cost of Illness Risk Factors Epidemiology Health care Prevalence medicine Humans Age of Onset Young adult Adult atopic dermatitis Aged Aged 80 and over business.industry Health Care Costs Atopic dermatitis Middle Aged medicine.disease United States 030104 developmental biology Immunology Age of onset business |
Zdroj: | Clinics in Dermatology. 36:595-605 |
ISSN: | 0738-081X |
DOI: | 10.1016/j.clindermatol.2018.05.007 |
Popis: | Atopic dermatitis (AD) is driven by a complex gene-environment interaction. Many of the risk factors and genetic underpinning previously observed for pediatric AD may not apply to adult atopic dermatitis, suggesting that these may largely be different disorders. Whereas AD is classically thought of as a pediatric disease, recent studies have shown high rates of disease in adults as well. Risk factors for persistence of childhood-onset AD, as well as adult-onset AD, are reviewed. Adults with AD are particularly vulnerable to exogenous insults from the outside environment, including climate, ultraviolet exposure, pollution, irritants and pruritogens, and microbes. Finally, adult AD is associated with a substantial health care burden, with increased utilization, direct and indirect costs of care, and lost work productivity. |
Databáze: | OpenAIRE |
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