Including surrounding tissue improves ultrasound-based 3D mechanical characterization of abdominal aortic aneurysms
| Autor: | Niels J. Petterson, Marc R.H.M. van Sambeek, Richard G.P. Lopata, Frans N. van de Vosse, Emiel M.J. van Disseldorp |
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| Přispěvatelé: | Cardiovascular Biomechanics, Eindhoven MedTech Innovation Center |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
Materials science 0206 medical engineering Biomedical Engineering Biophysics 02 engineering and technology Shear modulus Stress (mechanics) 03 medical and health sciences 0302 clinical medicine medicine.artery Ultrasound Shear stress medicine Humans Orthopedics and Sports Medicine Aorta Abdominal Ultrasonography Speckle tracking Aorta business.industry Rehabilitation Models Cardiovascular Soft tissue medicine.disease 020601 biomedical engineering Arterial stiffness Abdominal aortic aneurysm Shear (sheet metal) cardiovascular system Female business Wall stress 030217 neurology & neurosurgery Biomedical engineering Aortic Aneurysm Abdominal |
| Zdroj: | Journal of Biomechanics, 85, 126-133. Elsevier |
| ISSN: | 0021-9290 |
| DOI: | 10.1016/j.jbiomech.2019.01.024 |
| Popis: | Objectives In this study the influence of surrounding tissues including the presence of the spine on wall stress analysis and mechanical characterization of abdominal aortic aneurysms using ultrasound imaging has been investigated. Methods Geometries of 7 AAA patients and 11 healthy volunteers were acquired using 3-D ultrasound and converted to finite element based models. Model complexity of externally unsupported (aorta-only) models was complemented with inclusion of both soft tissue around the aorta and a spine support dorsal to the aorta. Computed 3-D motion of the aortic wall was verified by means of ultrasound speckle tracking. Resulting stress, strain, and estimated shear moduli were analyzed to quantify the effect of adding surrounding material supports. Results An improved agreement was shown between the ultrasound measurements and the finite element tissue and spine models compared to the aorta-only models. Peak and 99-percentile Von Mises stress showed an overall decrease of 23–30%, while estimated shear modulus decreased with 12–20% after addition of the soft tissue. Shear strains in the aortic wall were higher in areas close to the spine compared to the anterior region. Conclusions Improving model complexity with surrounding tissue and spine showed a homogenization of wall stresses, reduction in homogeneity of shear strain at the posterior side of the AAA, and a decrease in estimated aortic wall shear modulus. Future research will focus on the importance of a patient-specific spine geometry and location. |
| Databáze: | OpenAIRE |
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