A Differential Diagnosis of Hyperalgesia, Toxicity, and Withdrawal from Intrathecal Morphine Infusion
| Autor: | Jianren Mao, Milan Stojanovic, Aneesh K. Singla, Lucy Chen |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Morphine
business.industry Clinical course Middle Aged Intrathecal Substance Withdrawal Syndrome Intrathecal morphine Diagnosis Differential Anesthesiology and Pain Medicine Opioid Hyperalgesia Anesthesia Toxicity medicine Humans Female Differential diagnosis medicine.symptom business Injections Spinal medicine.drug |
| Zdroj: | Anesthesia & Analgesia. 105:1816-1819 |
| ISSN: | 0003-2999 |
| DOI: | 10.1213/01.ane.0000290338.39037.38 |
| Popis: | Opioid-induced hyperalgesia, toxicity, and withdrawal are phenomena that may occur with intrathecal opioid infusion. We present a case in which a patient received intrathecal morphine infusion, and then experienced a clinical course that may have involved hyperalgesia, toxicity, and/or withdrawal. The possible differential diagnosis of opioid-induced hyperalgesia, toxicity, and withdrawal, and its implications in clinical pain management, are discussed. This report demonstrates the complexity of treating patients with long-term continuous intrathecal opioids when modest adjustment of the intrathecal cocktail results in a paradoxical clinical course. |
| Databáze: | OpenAIRE |
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