Role of depressive symptoms in the health-related quality of life of Venezuelan patients with rheumatoid arthritis. Results from a tertiary care center

Autor:	Soham Al Snih, Joanny C. Rey-Puente, Martin A. Rodriguez, Nardy N. Rivero-Carrera, Natali Serra-Bonett
Rok vydání:	2020
Předmět:	Male medicine.medical_specialty SF-36 Disease Arthritis Rheumatoid Tertiary Care Centers 03 medical and health sciences 0302 clinical medicine Quality of life Surveys and Questionnaires Internal medicine medicine Humans Depression (differential diagnoses) Depression business.industry 030503 health policy & services Public Health Environmental and Occupational Health Middle Aged Center for Epidemiologic Studies Depression Scale Venezuela humanities Rheumatology Cross-Sectional Studies Mood 030220 oncology & carcinogenesis Quality of Life Female 0305 other medical science business Body mass index
Zdroj:	Quality of Life Research. 29:2129-2136
ISSN:	1573-2649 0962-9343
Popis:	To examine the effect of depressive symptoms on health-related quality of life (HR-QoL) in Venezuelan patients with rheumatoid arthritis (RA). HR-QoL was assessed in a cross-sectional, single-center study of 212 consecutive Venezuelan patients with RA (1987 American College of Rheumatology criteria) using the Medical Outcomes Study Short Form (SF-36), which includes a Physical Composite Scale (PCS) and a Mental Composite Scale (MCS); depressive symptoms were assessed using the Center for Epidemiologic Studies Depression Scale. Covariates included socio-demographics, comorbidities, disease characteristics, body mass index, and disability. Unadjusted and multivariable linear regression analysis were used to determine the effect of depressive symptoms on HR-QoL. Mean age was 50.2 years and 89.6% were female. Twenty-five percent of patients had depressive symptoms. In the multivariable regression analysis, the presence of depressive symptoms changed the mental SF-36 scores by − 4.81 (p = 0.0052) and the physical SF-36 scores by − 3.33 (p = 0.0527). Other factors significantly associated with scores on the PCS of the SF-36 were functional class, disability and job loss due to RA. The presence of depressive symptoms negatively affected the HR-QoL in our patients, with a predominant effect on the MCS of the SF-36. The PCS of the SF-36 was mainly affected by those symptoms related to the functional impairment and inflammatory activity of the disease. The routine assessment and early treatment of depressive symptoms, targeting mental and mood manifestations, may improve the HR-QoL and thus contribute to healthier outcomes in Venezuelan RA patients.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b9c2c80c93d364aea9b488192fd5140 https://doi.org/10.1007/s11136-020-02485-7 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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