Neutrophil to lymphocyte ratio: a novel marker for predicting hospital mortality of patients with acute type A aortic dissection
| Autor: | Mehmed Yanartaş, Semi Ozturk, Mustafa Akçakoyun, Ahmet Gündeş, Cengiz Köksal, Ali Kemal Kalkan, Mehmet Altuğ Tuncer, Mehmet Yunus Emiroglu, Derya Ozturk, Ahmet Seyfeddin Gurbuz, Taner Iyigun, Mehmet Emin Kalkan |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Pathology Turkey Neutrophils Cross-sectional study Hospital mortality 030204 cardiovascular system & hematology Gastroenterology 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans Radiology Nuclear Medicine and imaging Hospital Mortality Lymphocytes Neutrophil to lymphocyte ratio Retrospective Studies Advanced and Specialized Nursing Aortic dissection business.industry fungi Retrospective cohort study General Medicine Aneurysm dissecting Middle Aged medicine.disease Hospitalization Aortic Dissection Cross-Sectional Studies Acute type 030220 oncology & carcinogenesis Female Cardiology and Cardiovascular Medicine business Safety Research |
| Zdroj: | Perfusion. 32:321-327 |
| ISSN: | 1477-111X 0267-6591 |
| DOI: | 10.1177/0267659115590625 |
| Popis: | Introduction: The inflammatory process has been reported to be associated with aortic dissection (AD) from the development to the prognosis. The aim of the study was to investigate a relationship between the neutrophil to lymphocyte ratio (NLR) and in-hospital outcomes in patients with acute aortic dissection (AAD) who underwent surgical repair. Methods: One hundred and eighty-four patients who were admitted with the diagnosis of type A AAD who underwent surgical repair at two large tertiary hospitals. According to their NLR, 91 patients had high NLR (>6.0) and 93 patients had low NLR (⩽6.0). Results: The frequency of major bleeding, hospital-related infection, multi-organ dysfunction and mortality in hospital were higher in the high NLR group compared to the low NLR group. NLR, WBC count and operation duration were found to be independent predictors for in-hospital mortality. Conclusions: The novel inflammatory marker NLR may be used to predict worse outcomes and hospital mortality in patients with AAD treated by surgical repair. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|