Acetazolamide-enhanced neuroSPECT scan reveals functional impairment after minimal traumatic brain injury not otherwise discernible
| Autor: | Elinor Goshen, S. Tzila Zwas, Chaim G. Pick, Omer Bonne, Gavriel Barkai, Ornah T. Dolberg, Shaul Schreiber |
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| Rok vydání: | 2004 |
| Předmět: |
Adult
Male Functional impairment Traumatic brain injury medicine.medical_treatment Neuroscience (miscellaneous) Neuropsychological Tests Single-photon emission computed tomography Personality Disorders Head trauma medicine Humans Radiology Nuclear Medicine and imaging Carbonic Anhydrase Inhibitors Tomography Emission-Computed Single-Photon medicine.diagnostic_test business.industry Valproic Acid Brain medicine.disease Acetazolamide Psychiatry and Mental health Regional Blood Flow Brain Injuries Anesthesia Concomitant Diuretic Cognition Disorders business Perfusion medicine.drug |
| Zdroj: | Psychiatry Research: Neuroimaging. 132:279-283 |
| ISSN: | 0925-4927 |
| Popis: | A patient suffering from aggressive personality changes and cognitive impairment following head trauma, without neurological or anatomical imaging findings, underwent neuroSPECT scans with and without acetazolamide injection, both before treatment and during treatment with valproate. Acetazolamide injection induced increased prefrontal perfusion not evident at baseline. Valproate treatment was associated with increased prefrontal perfusion concomitant with clinical improvement and abolished response to acetazolamide challenge. |
| Databáze: | OpenAIRE |
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