Impact of cardiovascular burden on coagulation pathway in apparently healthy women planning oocyte donation
| Autor: | Maria Elisabetta Coccia, Francesca Rizzello, Cinzia Fatini, Rita Paniccia, Monica Attanasio, Michela Cirillo |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Infertility
medicine.medical_specialty Physiology medicine.medical_treatment Group A Group B Physiology (medical) Coagulation testing Medicine Humans Risk factor Blood Coagulation Blood coagulation test Assisted reproductive technology Oocyte Donation business.industry Obstetrics Hematology medicine.disease Thrombelastography Hemostasis Female Blood Coagulation Tests Cardiology and Cardiovascular Medicine business Infertility Female |
| Zdroj: | Clinical hemorheology and microcirculation. 79(4) |
| ISSN: | 1875-8622 |
| Popis: | BACKGROUND: Hormonal fertility treatments are associated with increased coagulation factors inducing procoagulant milieu and possibly thrombotic risk. OBJECTIVE: To assess coagulation by ROTEM and coagulation tests in apparently healthy infertile women before oocyte donation procedure. METHODS: We enrolled 51 women (Assisted Reproductive Technology Centre, Florence). ROTEM and coagulation parameters were assessed before the start of infertility treatment. RESULTS: We divided women in 3 groups according to the number of cardiovascular risk factors: Group A (n = 10), Group B (n = 16), and Group C (n = 25). By considering ROTEM Extem test, a significantly increased of MCF, TPI, and G were observed in groups B (p = 0.005, p = 0.03, and p = 0.007) and C (p = 0.01, p = 0.05, and p = 0.005) in comparison to group A. As regards ROTEM Intem test, the TPI and G values were significantly higher in groups B and C in comparison to group A (p |
| Databáze: | OpenAIRE |
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