[A 10-year-old girl with anticardiolipin antibody, who showed bleeding tendency]
| Autor: | Yasuyo Kashiwagi, Keiko Kinoue, Hisashi Kawashima, Akinori Hoshika, Tooru Shimizu, Kouji Takekuma, Morio Arai |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
medicine.medical_specialty
Immunology Lupus nephritis Hemorrhage Gastroenterology immune system diseases Antiphospholipid syndrome Internal medicine medicine Immunology and Allergy Humans Lupus Erythematosus Systemic skin and connective tissue diseases Child Lupus anticoagulant Systemic lupus erythematosus medicine.diagnostic_test business.industry Glomerulonephritis General Medicine medicine.disease Antiphospholipid Syndrome Hyperfibrinolysis female genital diseases and pregnancy complications Antibodies Anticardiolipin Female Renal biopsy business Anti-SSA/Ro autoantibodies |
| Zdroj: | Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology. 19(3) |
| ISSN: | 0911-4300 |
| Popis: | We described a 10-year-old girl with SLE complicated with anticardiolipin antibody, who showed bleeding tendency since infant. Her platelet was 6 x 10(3)/microliter. The APTT was remarkably prolonged. The platelet count was normalized after steroid treatment. A false positive Venereal Disease Research Laboratory (VDRL) test, lupus anticoagulants and anticardiolipin antibodies (IgG and IgM) were positive. Her symptoms and the laboratory data fulfilled the criteria of antiphospholipid syndrome. Renal biopsy was performed because of proteinuria, hematuria and the positive of anti-nuclear antibody. The pathology of kidney showed that of lupus nephritis (diffuse membranous glomerulonephritis), and she was diagnosed SLE. She showed no laboratory findings of hyperfibrinolysis and no symptoms of thrombosis under the steroid treatment for 3 years. |
| Databáze: | OpenAIRE |
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