Prevalence and Clinical Significance of Occult Pulmonary Infection in Elderly Patients with Type 2 Diabetes Mellitus
| Autor: | Xiaobing Lai, Honghui Liao, Ping Huang, Xiaoyi Zheng, Jian Hua |
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| Rok vydání: | 2021 |
| Předmět: |
Lung Diseases
Male medicine.medical_specialty Article Subject Comorbidity Infections General Biochemistry Genetics and Molecular Biology Alzheimer Disease Risk Factors Internal medicine Diabetes mellitus Gram-Negative Bacteria Prevalence medicine Humans Infection control Clinical significance Aged Retrospective Studies General Immunology and Microbiology business.industry Type 2 Diabetes Mellitus Pneumonia General Medicine medicine.disease Occult Community-Acquired Infections Hospitalization Logistic Models Diabetes Mellitus Type 2 Etiology Medicine Female Occult pneumonia Gram-Negative Bacterial Infections business Research Article |
| Zdroj: | BioMed Research International BioMed Research International, Vol 2021 (2021) |
| ISSN: | 2314-6141 2314-6133 |
| DOI: | 10.1155/2021/3187388 |
| Popis: | The occult pulmonary infection is the most common complications in elderly patients with type 2 diabetes mellitus (T2DM). Since its etiological characteristics has not been clarified, infection control remains a serious problem for public health. To investigate the prevalence and clinical significance of occult pulmonary infection in elderly T2DM patients, in this study, 573 elderly patients cochallenged with T2DM and community-acquired pulmonary infection from January 2018 to December 2020 were selected in the hospitals and divided into occult pneumonia group (OP, n = 249 ) and nonoccult pneumonia group (NOP, n = 324 ) according to the nature of infection. Clinical medical records were analyzed retrospectively to summarize the infection characteristics of elderly diabetics with occult pneumonia. The prevalence of the cases (278/324, 85.8%) in NOP group was not higher than that in OP group (206/249, 82.7%; P > 0.05 ). Also, there was not significant difference in the distribution of isolated pathogens among the positive patients. The length of hospitalization and mortality of OP patients were significantly higher than those NOP patients. Multivariate logistic regression showed that advanced age, comorbidities, hypothyroidism, senile dementia, and prolonged bed rest were independent risk factors for occult pneumonia in elderly diabetic patients. Therefore, the results demonstrated that the pulmonary infection in elderly patients with diabetes mellitus is often occult. Gram-negative bacteria are the predominant pathogens and cause poor prognosis. Advanced age, comorbidities (senile dementia, hypothyroidism), and prolonged bed rest are the independent risk factors for occult pneumonia. |
| Databáze: | OpenAIRE |
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