Risk of childhood undernutrition related to small-for-gestational age and preterm birth in low- and middle-income countries
| Autor: | Chittaranjan S. Yajnik, Hong Yan, Jean H. Humphrey, Moira Donahue Angel, James M. Tielsch, Linda Richter, Reynaldo Martorell, Ayesha Sania, Lieven Huybregts, Fernando C. Barros, Sun Eun Lee, Parul Christian, Linda S. Adair, Per Ashorn, Caroline H.D. Fall, Enqing Liu, Lars Åke Persson, Patrick Kolsteren, Gang Hu, Wafaie W. Fawzi, Simon Kariuki, Wei Hao, Dominique Roberfroid, Lingxia Zeng, Charu V. Joglekar, Usha Ramakrishnan, Shams El Arifeen, Robert E. Black, Cesar G. Victora, David Osrin, Ghattu V. Krishnaveni, Feiko O. ter Kuile |
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| Přispěvatelé: | Other departments |
| Rok vydání: | 2013 |
| Předmět: |
Male
medicine.medical_specialty Pediatrics Epidemiology Birth weight Population Gestational Age Cohort Studies Pregnancy Risk Factors Humans Medicine Longitudinal Studies education Developing Countries Wasting reproductive and urinary physiology education.field_of_study Fetal Growth Retardation business.industry Obstetrics Malnutrition digestive oral and skin physiology Infant food and beverages nutritional and metabolic diseases Gestational age General Medicine Infant Low Birth Weight medicine.disease female genital diseases and pregnancy complications Premature birth Child Preschool Infant Small for Gestational Age Premature Birth Small for gestational age Female Underweight medicine.symptom business Infant Premature |
| Zdroj: | International journal of epidemiology, 42(5), 1340-1355. Oxford University Press |
| ISSN: | 1464-3685 0300-5771 |
| Popis: | Background Low- and middle-income countries continue to experience a large burden of stunting; 148 million children were estimated to be stunted, around 30–40% of all children in 2011. In many of these countries, foetal growth restriction (FGR) is common, as is subsequent growth faltering in the first 2 years. Although there is agreement that stunting involves both prenatal and postnatal growth failure, the extent to which FGR contributes to stunting and other indicators of nutritional status is uncertain. Methods Using extant longitudinal birth cohorts (n = 19) with data on birthweight, gestational age and child anthropometry (12–60 months), we estimated study-specific and pooled risk estimates of stunting, wasting and underweight by small-for-gestational age (SGA) and preterm birth. Results We grouped children according to four combinations of SGA and gestational age: adequate size-for-gestational age (AGA) and preterm; SGA and term; SGA and preterm; and AGA and term (the reference group). Relative to AGA and term, the OR (95% confidence interval) for stunting associated with AGA and preterm, SGA and term, and SGA and preterm was 1.93 (1.71, 2.18), 2.43 (2.22, 2.66) and 4.51 (3.42, 5.93), respectively. A similar magnitude of risk was also observed for wasting and underweight. Low birthweight was associated with 2.5–3.5-fold higher odds of wasting, stunting and underweight. The population attributable risk for overall SGA for outcomes of childhood stunting and wasting was 20% and 30%, respectively. Conclusions This analysis estimates that childhood undernutrition may have its origins in the foetal period, suggesting a need to intervene early, ideally during pregnancy, with interventions known to reduce FGR and preterm birth. |
| Databáze: | OpenAIRE |
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