Reduction of abdominal fat accumulation in rats by 8-week ingestion of a newly developed sweetener made from high fructose corn syrup
| Autor: | Ken Izumori, Tetsuo Iida, Tatsuhiro Matsuo, Reika Ishii, Takako Yamada, Kazuhiro Okuma, Noriko Hayashi |
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| Rok vydání: | 2012 |
| Předmět: |
Male
food.ingredient Starch Abdominal Fat Down-Regulation Fructose Carbohydrate metabolism Zea mays Analytical Chemistry chemistry.chemical_compound Blood serum food Ingestion Animals Humans Insulin Food science Obesity Rats Wistar Chemistry High-fructose corn syrup Body Weight food and beverages General Medicine Rats Corn syrup Glucose Blood chemistry Sweetening Agents Food Science |
| Zdroj: | Food chemistry. 138(2-3) |
| ISSN: | 1873-7072 |
| Popis: | Many studies have shown that ingestion of high-fructose corn syrup (HFCS) may cause an increase in body weight and abdominal fat. We recently developed a new sweetener containing rare sugars (rare sugar syrup; RSS) by slight isomerization of HFCS. Here, the functional effects of RSS on body weight and abdominal fat, and biochemical parameters in Wistar rats were examined. Rats (n=30) were randomly divided into three groups and maintained for 8-weeks on starch, starch+HFCS (50:50), and starch+RSS (50:50) diets. Rats in the Starch and HFCS groups gained significantly more body weight and abdominal fat than the RSS group. Fasting serum insulin in the RSS group was significantly lower than in the Starch and HFCS groups, although serum glucose in the HFCS and RSS groups was significantly lower than that in the Starch group. Thus, the substitution of HFCS with RSS prevents obesity induced by the consumption of HFCS. |
| Databáze: | OpenAIRE |
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