The impact of combined radiation and chemotherapy on outcome in uterine papillary serous carcinoma compared to chemotherapy alone
| Autor: | Benjamin Nutter, Sudha Amarnath, Fadi W. Abdul-Karim, Haider Mahdi, Peter G. Rose |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Oncology
medicine.medical_specialty endocrine system diseases medicine.medical_treatment Uterine serous carcinoma 03 medical and health sciences 0302 clinical medicine Uterine Corpus Drug Therapy Internal medicine medicine Carcinoma Humans Uterine Neoplasm Survival rate Neoplasm Staging Chemotherapy 030219 obstetrics & reproductive medicine Hysterectomy Radiation business.industry Overall Survival Peritoneal Cytology Obstetrics and Gynecology Uterine Serous Carcinoma General Medicine medicine.disease Disease-Specific Survival Combined Modality Therapy Cystadenocarcinoma Serous Chemotherapy Adjuvant 030220 oncology & carcinogenesis Uterine Neoplasms Original Article business Adjuvant Chemoradiotherapy |
| Zdroj: | Journal of Gynecologic Oncology |
| ISSN: | 2005-0399 2005-0380 |
| Popis: | Objective To investigate the impact of pelvic radiation on survival in patients with uterine serous carcinoma (USC) who received adjuvant chemotherapy. Methods Patients with stage I-IV USC were identified from the Surveillance, Epidemiology, and End Results program 2000 to 2009. Patients were included if treated with surgery and chemotherapy. Patients were divided into two groups: those who received chemotherapy and pelvic radiation therapy (CT_RT) and those who received chemotherapy only (CT). Kaplan-Meier curves and Cox regression proportional hazard models were used. Results Of the 1,838 included patients, 1,272 (69%) were CT and 566 (31%) were CT_RT. Adjuvant radiation was associated with significant improvement in overall survival (OS; p |
| Databáze: | OpenAIRE |
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