Topical application of lidocaine or bupivacaine in the healing of surgical wounds in dogs
| Autor: | Josiane Morais Pazzini, Guilherme Galhardo Franco, Elizabeth Regina Carvalho, Camila Potério Borsaro, Laura Zanato, Andresa Matsui, Fernando Yoiti Kitamura Kawamoto, Bruno Watanabe Minto |
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| Přispěvatelé: | Universidade Estadual Paulista (Unesp), União das Faculdades dos Grandes Lagos (UNILAGO) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
Lidocaine RD1-811 medicine.medical_treatment Surgical Wound Lesion 03 medical and health sciences 0302 clinical medicine Dogs Experimental Surgery Biopsy medicine Animals Anesthetics Local Saline Bupivacaine Wound Healing medicine.diagnostic_test business.industry Surgical wound Surgical Wounds medicine.anatomical_structure 030220 oncology & carcinogenesis Anesthesia Anesthetic Abdomen 030211 gastroenterology & hepatology Female Original Article Surgery medicine.symptom Analgesia business medicine.drug |
| Zdroj: | Acta Cirurgica Brasileira, Vol 35, Iss 7 (2020) Acta Cirurgica Brasileira, Volume: 35, Issue: 7, Article number: e202000701, Published: 14 AUG 2020 Acta Cirúrgica Brasileira v.35 n.7 2020 Acta Cirúrgica Brasileira Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) instacron:SBDPC Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP |
| ISSN: | 0102-8650 |
| Popis: | Made available in DSpace on 2020-12-12T02:19:28Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01. Added 1 bitstream(s) on 2021-07-15T15:07:31Z : No. of bitstreams: 1 S0102-86502020000700202.pdf: 1271415 bytes, checksum: c144bd441961978a16a10b65dc792425 (MD5) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Purpose: To analyze the anesthetic drugs interference with wound healing when used in the surgical bed. Methods: Macro and microscopic aspects of healing of surgical wounds were evaluated after instillation of topical anesthetics without vasoconstrictor or saline solution 0.9% as control in the transsurgical period. Thirty dogs, males and females were divided into two experimental groups. In both groups, two circular punch lesions of 6 mm diameter were performed in the abdomen. In group 1, lidocaine was instilled in one of the lesions and saline solution in the contralateral lesion. In group 2 the procedure was repeated with the use of bupivacaine. The macroscopic assessment of the lesions was performed on the first, third and tenth postoperative day. The excisional biopsy was performed on the tenth day and the samples were submitted for histopathological examination. Results: The macroscopic analysis had a significant difference between groups. Microscopic analysis was not significant between groups. Conclusions: The topical application of lidocaine and bupivacaine in the surgical wound is feasible and it does not influence skin healing. The benefit of such a practice, which has been the subject of other studies, seems to outweigh the risks. Department of Clinical and Veterinary Surgery Faculdade de Ciências Agrárias e Veterinárias Universidade Estadual Paulista (FCAV-UNESP) FCAV-UNESP União das Faculdades dos Grandes Lagos (UNILAGO) Department of Clinical and Veterinary Surgery Faculdade de Ciências Agrárias e Veterinárias Universidade Estadual Paulista (FCAV-UNESP) FCAV-UNESP FAPESP: 2015/24955-5 |
| Databáze: | OpenAIRE |
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