Nickel-Catalyzed Diastereoselective Reductive Cross-Coupling of Disubstituted Cycloalkyl Iodides with Aryl Iodides

Autor:	Zhi-Liang Shen, Xuan-Di Song, Meng-Meng Guo, Shuang Xu, Xue-Qiang Chu, Xiaocong Zhou, Mengtao Ma, Chuanji Shen
Rok vydání:	2021
Předmět:	010405 organic chemistry Aryl Organic Chemistry chemistry.chemical_element 010402 general chemistry 01 natural sciences Biochemistry Medicinal chemistry 0104 chemical sciences Catalysis chemistry.chemical_compound Nickel chemistry Functional group Physical and Theoretical Chemistry
Zdroj:	Organic Letters. 23:5118-5122
ISSN:	1523-7052 1523-7060
DOI:	10.1021/acs.orglett.1c01649
Popis:	A nickel-catalyzed direct reductive cross-coupling of disubstituted cycloalkyl iodides with aryl iodides was developed. The one-pot reaction, which is simple to operate, was capable of proceeding efficiently in a stereocontrolled manner to afford a variety of cross-coupled products with high diastereoselectivity and wide functional group tolerance.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b7a89f16ad6d2c3bbe9e5e1df1ee782 https://doi.org/10.1021/acs.orglett.1c01649 Zobrazit plný text záznamu