Evaluation of the Corneal Test as a Laboratory Method for Rabies Diagnosis
Autor: | O. P. Larghi, E. González L, J. R. Held |
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Rok vydání: | 1973 |
Předmět: |
Pathology
medicine.medical_specialty Rabies Fluorescent Antibody Technique Biology Immunofluorescence staining medicine.disease_cause General Biochemistry Genetics and Molecular Biology Cornea Diagnosis Differential Mice Dogs Methods medicine Animals Humans Horses General Pharmacology Toxicology and Pharmaceutics Antigens Viral Clinical Microbiology and Immunology Laboratory methods General Immunology and Microbiology Rabies virus Brain General Medicine medicine.disease Rats Staining medicine.anatomical_structure Evaluation Studies as Topic Immunology Cats Cattle Rabbits Differential diagnosis |
Zdroj: | Applied Microbiology. 25:187-189 |
ISSN: | 0003-6919 |
DOI: | 10.1128/am.25.2.187-189.1973 |
Popis: | The corneal test (CT) for rabies diagnosis was evaluated in samples from 313 subjects of different species. Some of the subjects were inoculated experimentally and others were naturally infected. When the CT was compared with immunofluorescence staining and mouse inoculation tests on brains of the same subjects, a sensitivity of 41.7% and a specificity of 100% were found. The authors conclude that a positive CT result would confirm the diagnosis of rabies, but a negative one would not exclude the possibility of disease. |
Databáze: | OpenAIRE |
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