Heterogeneity analysis of triphasic CT scan perfusion parameters in differential diagnosis of hepatocellular carcinoma and hemangioma
| Autor: | Guodong Pang, Fang Zhao, Guangrui Shao, Hai Zhong, Chunchun Shao, Zuyun Duan |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Carcinoma Hepatocellular Observational Study heterogeneity analysis 030218 nuclear medicine & medical imaging Lesion Hemangioma Diagnosis Differential 03 medical and health sciences 0302 clinical medicine Hepatic Artery Reference Values medicine Carcinoma Humans cardiovascular diseases Aged Retrospective Studies business.industry Portal Vein Liver Neoplasms histogram analysis Retrospective cohort study General Medicine hepatocellular carcinoma Middle Aged medicine.disease computed tomography perfusion imaging digestive system diseases eye diseases body regions medicine.anatomical_structure hemangioma 030220 oncology & carcinogenesis Hepatocellular carcinoma Female Radiology sense organs medicine.symptom Differential diagnosis business Tomography X-Ray Computed Perfusion Artery Research Article |
| Zdroj: | Medicine |
| ISSN: | 1536-5964 |
| Popis: | This study is to investigate quantitative measures and heterogeneity of perfusion parameters in the differential diagnosis of hepatocellular carcinoma (HCC) and hemangioma. In total, 32 HCC and 44 hemangioma (types 1, 2, and 3) cases were included in this retrospective study. Hepatic artery coefficient (HAC), portal vein coefficient (PVC), and arterial enhancement fraction (AEF) were calculated. Tumor heterogeneity was analyzed. Perfusion parameters and corresponding percentiles were compared between the HCC and hemangioma (especially atypical hemangioma) cases, as well as between the substantial lesion part and surrounding normal tissue. The mean value, and the 10th, 50th, 75th, and 90th percentiles of PVC were significantly lower in the HCC cases than the types 1 and 2 hemangioma cases (P .05). Quantitative measurement of perfusion parameters and heterogeneity analysis show significance differences in the early detection and differential diagnosis of HCC and hemangioma cases, which might contribute to increasing the diagnostic accuracy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|