Fluorescent sodium ion indicators based on the 1,7-diaza-15-crown-5 system
| Autor: | Zhenjun Diwu, Vladimir Martin, Kyle R. Gee, Anca Rothe |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Cation binding
Fluorophore Sodium Clinical Biochemistry Inorganic chemistry Pharmaceutical Science chemistry.chemical_element Biochemistry chemistry.chemical_compound Mice 15-Crown-5 Crown Ethers Drug Discovery Animals Chelation Molecular Biology Fluorescent Dyes Ionophores Organic Chemistry Water General Medicine Cations Monovalent Combinatorial chemistry Fluorescence Solutions Spectrometry Fluorescence chemistry Reagent NIH 3T3 Cells Molecular Medicine Selectivity |
| Zdroj: | Bioorganicmedicinal chemistry letters. 14(21) |
| ISSN: | 0960-894X |
| Popis: | A series of novel sodium ion-sensitive fluorescent reagents suitable for biological applications is described. The chelator nitrogen atom substituents affect the selectivity and affinity of cation binding, while the nature of the fluorophore determines the type of fluorescent response to metal ion chelation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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