| Autor: |
Hegazy, Ahmed N., Krönke, Jan, Angermair, Stefan, Schwartz, Stefan, Weidinger, Carl, Keller, Ulrich, Treskatsch, Sascha, Siegmund, Britta, Schneider, Thomas |
| Rok vydání: |
2022 |
| DOI: |
10.6084/m9.figshare.20057457 |
| Popis: |
Additional file 1: Figure S1. (A) Clinical timeline highlighting the initiated hematological treatments of APL before SARS-CoV-2 detection in nasopharyngeal swabs. (B) Faggot cells with multiple Auer rods (arrow mark) in bone marrow aspirate. Blood differential tests (C), hemoglobin and LDH (D), and vital signs including blood pressure, heart rate, and oxygen saturation (E) from admission to casirivimab/imdevimab infusion. Normal ranges are highlighted in green. Figure S2. Chest X-rays along the clinical course from diagnosis of acute promyelocytic leukemia (APL) to CRS after casirivimab/imdevimab infusion and subsequent period in the ICU. Figure S3. (A) Clinical timeline highlighting the initiated treatments in the ICU after casirivimab/imdevimab infusion. (B) Complete blood count after ICU admission. (C) Flow cytometric analysis of peripheral blood after ICU admission including CD3 T cell characterization. Normal ranges are highlighted in green. Table S1. Microbiological laboratory assessment from diagnosis of acute APL to CRS after casirivimab/imdevimab treatment and during the ICU stay. (A) Microbiological culture performed on different patient-derived materials. (B) Microbiological assays for the analysis of certain pathogens. Table S2. Virological laboratory assessment from diagnosis of acute APL to CRS after casirivimab/imdevimab treatment and during the ICU stay. (A) SARS-CoV-2 molecular diagnostics including RT-PCR and virus sequencing at different time points. (B) Serological assessment of the immune status to different viruses. (C) PCR detection of various viruses in blood and bronchoalveolar lavage. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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