Water and exchangeable sodium in Goldblatt two-kidney, two-clip hypertensive rats
| Autor: | F M Santoro, M. K. Maquieira, I J de la Riva, S Morera, María Inés Rosón, M. A. Mendez, W.P. Mac Cormack |
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| Rok vydání: | 1986 |
| Předmět: |
Male
medicine.medical_specialty Radioisotope Dilution Technique Sodium Body water chemistry.chemical_element Adipose tissue Renovascular hypertension Two kidney Body Water medicine.artery Internal medicine Internal Medicine Extracellular Medicine Animals Renal artery business.industry Body Weight Rats Inbred Strains Water-Electrolyte Balance medicine.disease Rats Endocrinology Hypertension Renovascular chemistry Adipose Tissue Lean body mass business Extracellular Space |
| Zdroj: | Clinical and experimental hypertension. Part A, Theory and practice. 8(8) |
| ISSN: | 0730-0077 |
| Popis: | Exchangeable 22Na (ExNa), total body water (TBW) and the inulin space (InSp) were determined in two-kidney, two-clip (2K-2C) hypertensive and sham operated (normotensive) control rats 6-8 weeks after surgery. TBW (ml/kg lean body weight) was the same in hypertensive and sham rats. In contrast, ExNa (mEq/kglbw) and InSp (ml/kglbw) significantly increased (p less than 0.01) in rats whose hypertension did not exceed 170 mmHg. Consequently, sham, moderate hypertensive (less than 170 mmHg) and severe hypertensive (less than 170 mmHg) animals showed equal TBW but differed in body water distribution in that moderately hypertensive animals displayed a redistribution of water in favor of the extracellular space. |
| Databáze: | OpenAIRE |
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