Cystoid macular edema: a correlation between macular volumetric parameters and visual acuity

Autor: Michael Mimouni, Dov Weinberger, Anna Levant, Yoav Nahum, Boris Levant
Rok vydání: 2013
Předmět:
Zdroj: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie. 49(2)
ISSN: 1715-3360
Popis: Objective To study in patients with cystoid macular edema (CME) the correlation between macular volumetric parameters on ocular coherence tomography (OCT) and visual acuity (VA). Design A retrospective consecutive cohort design was used. Participants The sample included 167 examinations of 92 consecutive patients (130 eyes). Methods Patients underwent spectral-domain OCT for CME from the years 2008 to 2010 at a tertiary medical centre. Background and VA data were recorded from the files. The custom-developed Cystometer software was used to calculate volumetric parameters from the OCT videos. Results In univariate analyses, VA correlated best with cystoid macular volume (CMVol; R 2 = 8.57) and total macular volume (TMV; R 2 = 7.46). By underlying disease, the strongest correlation was found with CMVol ( R 2 = 8.47) in patients with diabetic CME (n = 91) and with TMV ( R 2 = 22.18) in patients with branch retinal vein occlusion (n = 46). In multiple regression analyses, TMV, age, and CMVol/TMV accounted for 17.57% of the variation in VA. In the diabetic CME group, CMVol/TMV and age accounted for 15.34% of the variation; in the branch retinal vein occlusion group, TMV accounted for 22.18% of the variation. Conclusions Macular volumetric parameters measured by OCT and Cystometer software significantly correlate with VA in patients with CME, with variations by underlying CME causative factor.
Databáze: OpenAIRE