Irisin level in type 2 diabetic patients and its relation to glycemic control and diabetic complications

Autor:	Elham M. Yousief, Ahmed Ramadan, Dalia R. Ibrahim, Heba Sedrak, Hemmat E. El Haddad, Mervat Hussin, Rasha M. Abdel Samie
Rok vydání:	2019
Předmět:	medicine.medical_specialty Diabetic neuropathy business.industry Endocrinology Diabetes and Metabolism Adipokine Diabetic retinopathy medicine.disease Gastroenterology Insulin resistance Intima-media thickness Diabetes mellitus Internal medicine Internal Medicine medicine business Body mass index Glycemic
Zdroj:	International Journal of Diabetes in Developing Countries. 39:641-646
ISSN:	1998-3832 0973-3930
Popis:	Irisin is a new myokin and adipokine related to human obesity and insulin resistance status. To investigate whether serum irisin is related to glycemic indicators and micro and macrvascular complications in patients with T2DM. The study included 60 T2DM patients and 30 healthy controls. Anthropometric measures, neurological assessment, and fundus examination were done to all patients. Correlations of serum irisin and blood glucose, glycosylated hemoglobin (HbA1C), urinary albumin, estimated glomerular filtration rat (eGFR), C-reactive protein (CRP), and carotid intima media thickness (CIMT) were analyzed using Spearman’s correlation coefficient. In diabetic patients, there was negative correlation between irisin level and duration of diabetes(r = − 0.302, p = 0.023), body mass index (BMI) (r = − 0.663, p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b4460ed276b8862a7af8ffbbc69cc51 https://doi.org/10.1007/s13410-019-00717-2 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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