Self-measurement of blood pressure at home reduces the need for antihypertensive drugs: a randomized, controlled trial
| Autor: | Paul-Hugo M. van der Kuy, Frank W. Beltman, Diederick E. Grobbee, Daniëlle E. M. Brunenberg, Patricia J. Nelemans, Peter W. de Leeuw, Manuela A. Joore, Abraham A. Kroon, Andries J. Smit, Alfons G.H. Kessels, Gert A. van Montfrans, Jacques W.M. Lenders, Roger J M W Rennenberg, Theo Thien, Carmen D. Dirksen, Willem J. Verberk |
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| Přispěvatelé: | Pharmacy, Internal Medicine, Groningen Kidney Center (GKC), Vascular Ageing Programme (VAP), ACS - Amsterdam Cardiovascular Sciences, General Internal Medicine |
| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
Ambulatory blood pressure Health aging / healthy living [IGMD 5] hypertension Urinary system self-measurements Diastole Vascular medicine and diabetes [UMCN 2.2] Prehypertension RECOMMENDATIONS law.invention PROPOSAL Randomized controlled trial law HYPERTENSIVE PATIENTS Internal medicine Internal Medicine Medicine home monitoring GENERAL-POPULATION JAPAN Cardiovascular diseases [NCEBP 14] treatment business.industry OFFICE MORTALITY blood pressure medicine.disease EUROPEAN-SOCIETY REFERENCE VALUES Surgery Blood pressure OHASAMA Ambulatory Cardiology Microalbuminuria ambulatory blood pressure measurement business |
| Zdroj: | Hypertension, 50(6), 1019-1025. Lippincott Williams & Wilkins Hypertension, 50, 1019-25 Hypertension, 50(6), 1019-1025. LIPPINCOTT WILLIAMS & WILKINS Hypertension, 50(6), 1019-1025. Lippincott Williams and Wilkins Hypertension, 50, 6, pp. 1019-25 |
| ISSN: | 0194-911X |
| Popis: | It is still uncertain whether one can safely base treatment decisions on self-measurement of blood pressure. In the present study, we investigated whether antihypertensive treatment based on self-measurement of blood pressure leads to the use of less medication without the loss of blood pressure control. We randomly assigned 430 hypertensive patients to receive treatment either on the basis of self-measured pressures (n=216) or office pressures (OPs; n=214). During 1-year follow-up, blood pressure was measured by office measurement (10 visits), ambulatory monitoring (start and end), and self-measurement (8 times, self-pressure group only). In addition, drug use, associated costs, and degree of target organ damage (echocardiography and microalbuminuria) were assessed. The self-pressure group used less medication than the OP group (1.47 versus 2.48 drug steps; P P P =0.25/0.20), in changes in left ventricular mass index (−6.5 g/m 2 versus −5.6 g/m 2 ; P =0.72), or in median urinary microalbumin concentration (−1.7 versus −1.5 mg per 24 hours; P =0.87). Nevertheless, 24-hour ambulatory blood pressure values at the end of the trial were higher in the self-pressure than in the OP group: 125.9 versus 123.8 mm Hg ( P P |
| Databáze: | OpenAIRE |
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