Postglacial migration shaped the genomic diversity and global distribution of the wild ancestor of lager-brewing hybrids

Autor: David Peris, Kayla Sylvester, Diego Libkind, Chris Todd Hittinger, Dana A. Opulente, Christian A. Lopes, Quinn K. Langdon, Kelly V. Buh, Maria E. Rodriguez, Martin Jarzyna, Juan I. Eizaguirre
Přispěvatelé: National Science Foundation (US), National Institute of Food and Agriculture (US), European Commission, Fondo para la Investigación Científica y Tecnológica (Argentina), Universidad Nacional del Comahue
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Cancer Research
DIVERSITY
BEER
Yeast and Fungal Models
QH426-470
Geographical locations
Gene flow
purl.org/becyt/ford/1 [https]
0302 clinical medicine
Refugium (population biology)
10. No inequality
Genetics (clinical)
Nucleotide sequencing
Species diversity
0303 health sciences
Geography
Ecology
Saccharomyces eubayanus
Eukaryota
Europe
PATAGONIA
Phylogeography
Biogeography
Experimental Organism Systems
Sympatric speciation
Saccharomyces Cerevisiae
Genome
Fungal
Research Article
Ecological Metrics
Nucleotide Sequencing
Saccharomyces cerevisiae
Biology
Research and Analysis Methods
Evolution
Molecular
03 medical and health sciences
Saccharomyces
Holarctic
Model Organisms
Genetics
purl.org/becyt/ford/1.6 [https]
Molecular Biology Techniques
Sequencing Techniques
Molecular Biology
Ecology
Evolution
Behavior and Systematics
Ecosystem
030304 developmental biology
Genetic diversity
Evolutionary Biology
Polymorphism
Genetic
Population Biology
Ecology and Environmental Sciences
Organisms
Fungi
Biology and Life Sciences
Species Diversity
15. Life on land
South America
biology.organism_classification
Yeast
SACCHARMYCES EUBAYANUS
Evolutionary biology
Earth Sciences
Animal Studies
Hybridization
Genetic
People and places
030217 neurology & neurosurgery
Population Genetics
Zdroj: PLoS Genetics, Vol 16, Iss 4, p e1008680 (2020)
PLoS Genetics
Digital.CSIC. Repositorio Institucional del CSIC
instname
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
ISSN: 1553-7404
1553-7390
Popis: The wild, cold-adapted parent of hybrid lager-brewing yeasts, Saccharomyces eubayanus, has a complex and understudied natural history. The exploration of this diversity can be used both to develop new brewing applications and to enlighten our understanding of the dynamics of yeast evolution in the wild. Here, we integrate whole genome sequence and phenotypic data of 200 S. eubayanus strains, the largest collection known to date. S. eubayanus has a multilayered population structure, consisting of two major populations that are further structured into six subpopulations. Four of these subpopulations are found exclusively in the Patagonian region of South America; one is found predominantly in Patagonia and sparsely in Oceania and North America; and one is specific to the Holarctic ecozone. Plant host associations differed between subpopulations and between S. eubayanus and its sister species, Saccharomyces uvarum. S. eubayanus is most abundant and genetically diverse in northern Patagonia, where some locations harbor more genetic diversity than is found outside of South America, suggesting that northern Patagonia east of the Andes was a glacial refugium for this species. All but one subpopulation shows isolation-by-distance, and gene flow between subpopulations is low. However, there are strong signals of ancient and recent outcrossing, including two admixed lineages, one that is sympatric with and one that is mostly isolated from its parental populations. Using our extensive biogeographical data, we build a robust model that predicts all known and a handful of additional regions of the globe that are climatically suitable for S. eubayanus, including Europe where host accessibility and competitive exclusion by other Saccharomyces species may explain its continued elusiveness. We conclude that this industrially relevant species has rich natural diversity with many factors contributing to its complex distribution and natural history.
This material is based upon work supported by the National Science Foundation (https://www.nsf.gov) under Grant Nos. DEB-1253634 (to CTH) and DGE-1256259 (Graduate Research Fellowship to QKL), the USDA National Institute of Food and Agriculture (https://www.nifa.usda.gov) Hatch Project Nos. 1003258 and 1020204 to CTH, and in part by the DOE Great Lakes Bioenergy Research Center (DOE BER Office of Science (https://www.energy.gov/science/office-science) Nos. DE-SC0018409 and DE-FC02-07ER64494 to Timothy J. Donohue). QKL was also supported by the Predoctoral Training Program in Genetics, funded by the National Institutes of Health (5T32GM007133, https://www.nih.gov). DP is a Marie Sklodowska-Curie fellow of the European Union’s Horizon 2020 (https://ec.europa.eu/programmes/horizon2020/en) research and innovation program (Grant Agreement No. 747775). DL was supported by CONICET (PIP11220130100392CO, https://www.conicet.gov.ar), FONCyT (PICT 3677, PICT 2542, https://www.argentina.gob.ar/ciencia/agencia/fondo-para-la-investigacion-cientifica-y-tecnologica-foncyt), Universidad Nacional del Comahue (B199, https://www.uncoma.edu.ar), and NSF-CONICET grant (https://www.conicet.gov.ar). CTH is a Pew Scholar in the Biomedical Sciences and H. I. Romnes Faculty Fellow, supported by the Pew Charitable Trusts (https://www.pewtrusts.org/en) and Office of the Vice Chancellor for Research and Graduate Education (https://research.wisc.edu) with funding from the Wisconsin Alumni Research Foundation (WARF, https://www.warf.org), respectively.
Databáze: OpenAIRE
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