Transfusion dans l’autogreffe et l’allogreffe de cellules souches hématopoïétiques chez l’adulte et l’enfant : recommandations de la Société francophone de greffe de moelle et de thérapie cellulaire (SFGM-TC)

Autor: Jean-Baptiste Thibert, Laurent Bardiaux, Olga Samsonova, Frédéric Garban, Bénédicte Debiol, Yohan Desbrosses, Thi Ngoc Phuong Huynh, Ibrahim Yakoub-Agha, Tamim Alsuliman, Bénédicte Bruno, Christine Giraud
Přispěvatelé: Centre hospitalier universitaire de Poitiers (CHU Poitiers), Etablissement français du sang [Rennes] (EFS Bretagne), Service d'Hématologie [CHRU Besançon], Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Lille Inflammation Research International Center - U 995 (LIRIC), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Hôpital Purpan [Toulouse], CHU Toulouse [Toulouse]
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Bulletin du Cancer
Bulletin du Cancer, 2019, 106, pp.S52-S58. ⟨10.1016/j.bulcan.2018.08.016⟩
Bulletin du Cancer, John Libbey Eurotext, 2019, 106, pp.S52-S58. ⟨10.1016/j.bulcan.2018.08.016⟩
ISSN: 0007-4551
1769-6917
DOI: 10.1016/j.bulcan.2018.08.016⟩
Popis: The recommendations of the French Health and Drug Safety Authorities (HAS/ANSM-Haute Autorite de sante/Agence nationale de securite du medicament) are known, but there are always new developments underway. With regards to CMV suppression, there is the introduction of platelet glycoprotein Ia and the Intercept (Amotosalem+UVA) inactivation method which addresses bacterial risk. The irradiation of platelets is included in the recommendations to ensure HEV-negative plasma post allograft. In terms of blood transfusion safety, these measures as well as the broader spectrum of Ia, particularly for arboviruses, are a real breakthrough. The survey conducted in clinical services and the services providing blood products for transfusion along with a literature review have shown that several improvements need to be made. The first is a reduction of transfusions of concentrated red blood cells with introduction at a threshold of 7g/dL during hospitalization of patients without a fragile clinical status. The second improvement would address transfusion of refractory thrombocytopenia, encouraging an increase in discussion between clinicians and those conducting the transfusion in order to consider different etiologies and to identify appropriate care protocols. Third would be the need for the transmission of information between the transplantation doctors and blood transfusion specialists in order to define an approach to transfusion care adapted to the patient's situation. It is important to inform and educate patients about transfusion protocols post allotransplant or autotransplant. It must be clearly communicated to patients that they should always have on their person their blood group documentation. This is especially true when receiving care for a hemopathy or an autologous transplant. If undergoing an allogeneic transplant, patients should also carry transfusion guidelines post autotransplant or post allotransplant along with the phone numbers for the stem cell transplantation department and the blood transfusion center responsible for their care.
Databáze: OpenAIRE
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