The relationship of blood pressure with uric acid and bilirubin in young lean and overweight/obese men and women: the African-PREDICT study
Autor: | Wessel L. Du Toit, Aletta E. Schutte, Catharina M. C. Mels |
---|---|
Přispěvatelé: | 10922180 - Schutte, Aletta Elisabeth, 12076341 - Mels, Catharina Martha Cornelia, 26342235 - Du Toit, Wikus L. |
Rok vydání: | 2019 |
Předmět: |
Bilirubin
business.industry nutritional and metabolic diseases Physiology 030204 cardiovascular system & hematology Overweight medicine.disease Obesity 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Blood pressure chemistry Hypertension Internal Medicine medicine Arterial stiffness Uric acid 030212 general & internal medicine medicine.symptom business Body mass index Pulse wave velocity |
Zdroj: | Journal of Human Hypertension. 34:648-656 |
ISSN: | 1476-5527 0950-9240 |
DOI: | 10.1038/s41371-019-0287-7 |
Popis: | Mounting evidence supports the central role of oxidative stress and inflammation in obesity and the development of hypertension. However, most studies focusing on the non-enzymatic antioxidants, such as uric acid and bilirubin, and their relationship with obesity and hypertension were done in older populations with overt cardiovascular disease. The aim of this study was therefore to compare measures of cardiovascular function (blood pressure and arterial stiffness) and non-enzymatic antioxidants (uric acid and bilirubin) between young healthy lean and overweight/obese men and women and to investigate the link between these variables. We grouped 967 men and women (aged 20–30 years) according to body mass index (BMI) categories (lean BMI |
Databáze: | OpenAIRE |
Externí odkaz: |