Successful use of ivermectin in the treatment of endemic scabies in a nursing home

Autor: Geoffrey Watt, John R Sullivan, Brent J Barker
Rok vydání: 1997
Předmět:
Zdroj: Australasian Journal of Dermatology. 38:137-140
ISSN: 1440-0960
0004-8380
DOI: 10.1111/j.1440-0960.1997.tb01130.x
Popis: Ivermectin, an antiparasitic agent, was successfully used as a sole agent to combat endemic scabies in a closed 33-bed ward of a rural nursing home. Previous topical therapies, including multiple applications of permethrin, gamma-benzene hexachloride, benzyl benzoate and precipitated sulfur in white soft paraffin, had failed. Several patients exhibited hyperkeratotic crusted scabies with head and neck involvement and all residents except one recently arrived resident had evidence of active infestation. All residents were treated with 200 micrograms/kg of ivermectin and this dose was repeated 2 weeks later in all subjects. Four weeks after the first dose of ivermectin there was no evidence of active scabies and all rashes were totally resolved by 6 weeks. The action of ivermectin, its safety and its indications are discussed.
Databáze: OpenAIRE