Tumor thrombus involving the inferior vena cava in renal malignancy: is there a difference in clinical presentation and outcome among right and left side tumors?
Autor: | Mark S. Soloway, Gaetano Ciancio, Devendar Katkoori, Manoharan Murugesan |
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Jazyk: | angličtina |
Rok vydání: | 2009 |
Předmět: |
Male
medicine.medical_specialty Urology medicine.medical_treatment Malignancy lcsh:RC870-923 Inferior vena cava Disease-Free Survival Renal cell carcinoma medicine nephrectomy Humans kidney neoplasms Neoplasm Invasiveness Thrombus Neoplasm Staging Retrospective Studies Venous Thrombosis business.industry Retrospective cohort study Middle Aged medicine.disease lcsh:Diseases of the genitourinary system. Urology Nephrectomy Surgery medicine.vein vena cava inferior thrombectomy Laterality cardiovascular system Female Radiology Neoplasm Recurrence Local Renal vein business Follow-Up Studies |
Zdroj: | International Brazilian Journal of Urology, Vol 35, Iss 6, Pp 652-657 (2009) International braz j urol, Volume: 35, Issue: 6, Pages: 652-657, Published: DEC 2009 International braz j urol v.35 n.6 2009 International Braz J Urol Sociedade Brasileira de Urologia (SBU) instacron:SBU |
ISSN: | 1677-6119 1677-5538 |
Popis: | PURPOSE: Renal cell carcinoma (RCC) has a propensity to propagate into the renal vein and inferior vena cava (IVC). Due to inherent differences in the venous anatomy of the right and left kidneys, tumor thrombus involvement of IVC may vary. The aim of this study is to compare clinical presentation and outcome of right vs. left RCC with IVC thrombus. MATERIALS AND METHODS: Patients who underwent radical nephrectomy and IVC thrombectomy between 1997 and 2008 were identified. All relevant data were collected and analyzed. Results: Eight-seven patients were included. Sixty patients (69%) had a right sided tumor. Mean tumor size was 10.2 (± 4) cm and was not significantly different on either side. Fifty-six percent of right sided tumors had level-III (intra-hepatic) or higher tumor thrombus, while 22% of left sided tumors had similar level thrombus extension (p < 0.0001). Nearly 50% of left sided tumors showed level-I thrombus compared to 10% of right side tumors. A comparison of age, estimated blood loss and transfusion rate was not significantly different. The recurrence free (p = 0.9) and disease specific survival (p = 0.4) were not significantly different between the right and left side tumors with IVC thrombus. Conclusion: A level-III IVC tumor thrombus is more frequently seen with a right side tumor. However, clinical and operative characteristics among the left and right sided tumors with IVC thrombus were not different. More significantly, recurrence rate and survival did not differ with the laterality of the tumor. |
Databáze: | OpenAIRE |
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