Childhood meningitis in Kuwait in the era of post pneumococcal conjugate vaccination: A multicenter study
| Autor: | Suha Atyani, Anfal Taher, Entesar H. Husain, Amna Alkoot, Abdullah Al-fraij, Abdulrahman Al-Daithan, May Alenezi, Talal AlSaleem, Hussain Sadeq |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Male Pediatrics medicine.medical_specialty 030106 microbiology Haemophilus Neisseria meningitidis medicine.disease_cause Group B Pneumococcal conjugate vaccine lcsh:Infectious and parasitic diseases Meningitis Bacterial Pneumococcal Vaccines 03 medical and health sciences 0302 clinical medicine Streptococcus pneumoniae Medicine Humans lcsh:RC109-216 030212 general & internal medicine Meningitis Aseptic Child Retrospective Studies Vaccines Conjugate business.industry Streptococcus lcsh:Public aspects of medicine Vaccination Infant Newborn Public Health Environmental and Occupational Health Aseptic meningitis Infant lcsh:RA1-1270 General Medicine medicine.disease Survival Analysis Infectious Diseases Kuwait Child Preschool Female business Meningitis medicine.drug |
| Zdroj: | Journal of Infection and Public Health, Vol 10, Iss 6, Pp 766-769 (2017) |
| ISSN: | 1876-0341 |
| DOI: | 10.1016/j.jiph.2016.11.009 |
| Popis: | This is a retrospective study to evaluate epidemiology and etiologies of childhood meningitis in Kuwait after the routine introduction of the pneumococcal conjugate vaccine. The data was collected from 196 patients in the period of 2010–2014. Aseptic meningitis accounted for 51% of the cases, bacterial meningitis accounted for 29% cases and partially treated meningitis were 20%. Organisms causing bacterial meningitis were: Streptococcus pneumoniae 40.4%, Neisseria meningitidis 17.6%, Haemophilus spp. 12.2%, other gram positive or negative 19.3%, and Group B Streptococcus 8.8%. The hospitalization was complicated by admission to the ICU in 16.3% patients. Sequelae on discharge were seen in 4%, and 2.5% died of complications of meningitis. In children with pneumococcal meningitis, 48% were admitted to the ICU, 35% were discharged with sequelae and 13% died. In the era of post pneumococcal conjugate vaccination, S. pneumoniae remains the leading cause of bacterial meningitis with the greatest morbidity and mortality. Keywords: Meningitis, Children, Pediatric, Pneumococcal conjugate vaccine, Vaccine, Kuwait |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|