Biomarkers in Parkinson’s disease: a funder’s perspective
| Autor: | Todd Sherer, Jamie L. Eberling, Mark Frasier, Sohini Chowdhury |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
Pathology Parkinson's disease Protein Deglycase DJ-1 Clinical Biochemistry tau Proteins Uric acid blood Disease Cytokines metabolism Drug Discovery medicine Humans Disease biomarker Intensive care medicine Oncogene Proteins business.industry Tumor Suppressor Proteins Biochemistry (medical) Perspective (graphical) Intracellular Signaling Peptides and Proteins food and beverages Parkinson Disease medicine.disease Glutathione Uric Acid alpha-Synuclein Cytokines Biomarker (medicine) α synuclein Carrier Proteins business Biomarkers |
| Zdroj: | Biomarkers in Medicine. 4:723-729 |
| ISSN: | 1752-0371 1752-0363 |
| Popis: | Therapeutic development in Parkinson’s disease is hampered by the paucity of well-validated biomarkers that can assist with diagnosis and/or tracking the progression of the disease. Since its inception, the Michael J Fox Foundation for Parkinson’s Research has invested heavily in biomarker research and continues to prioritize discovery and development efforts. This article summarizes the history and evolution of the Michael J Fox Foundation’s role in supporting biomarker research and lays out the current challenges in successfully developing markers that can be used to test therapies, while also providing a vision of future funding efforts in Parkinson’s disease biomarkers. |
| Databáze: | OpenAIRE |
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