Biphasic Epithelial Predominant Synovial Sarcoma Presenting as Painful Thigh Mass
| Autor: | Sahar Montazeri, Elham Mirzaian, Farbod Emami Yeganeh, Seyed Mohammad Tavangar |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Pathology medicine.medical_specialty Soft Tissue Neoplasm Cell CD99 Case Report Thigh Synovial sarcoma 03 medical and health sciences 0302 clinical medicine Thigh mass medicine RB1-214 Cuboidal Cell business.industry medicine.disease 030104 developmental biology medicine.anatomical_structure 030220 oncology & carcinogenesis Immunohistochemistry Epithelial predominant business |
| Zdroj: | Iranian Journal of Pathology Iranian Journal of Pathology, Vol 14, Iss 3, Pp 261-264 (2019) |
| ISSN: | 2345-3656 1735-5303 |
| Popis: | Synovial sarcomas are soft tissue neoplasms mostly located in the lower extremities of young adults. A case of synovial sarcoma of the thigh in a 35-year-old male with the predominant epithelial component is reported. Microscopically the tumor showed variable-sized well-differentiated glands lined by the cuboidal cells with small foci of spindle cell component between glandular structures. Immunohistochemically glandular components showed positivity for the pan CK and EMA while CD99 and TLE1 were positive in both glandular and spindle cell components. This type of synovial sarcoma could be indistinguishable from metastatic adenocarcinoma and malignant adnexal tumor, thus, immunohistochemistry and molecular studies play an essential role in the exact diagnosis of this type of tumor. |
| Databáze: | OpenAIRE |
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