Evaluation of Tissue Response to Gore-Tex (Expanded Polytetrafluoroethylene) Implantation
| Autor: | Gediz Murat Serin, Elif Aksoy, Senol Polat, Serdar Baylancicek, Selcuk Inanli, Yeşim Sağlican |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
Pathology H&E stain Biocompatible Materials Expanded polytetrafluoroethylene Prosthesis Implantation Rats Sprague-Dawley Subcutaneous Tissue Coated Materials Biocompatible Foreign-Body Migration Osteogenesis Periosteum Edema medicine Animals Animal study Polytetrafluoroethylene Inflammation Ossification business.industry Foreign-Body Reaction Synthetic graft General Medicine Rifamycins Anti-Bacterial Agents Rats Surgery medicine.anatomical_structure Otorhinolaryngology Granulation Tissue medicine.symptom business Complication |
| Zdroj: | Journal of Craniofacial Surgery. 24:1428-1430 |
| ISSN: | 1049-2275 |
| DOI: | 10.1097/scs.0b013e31828dcc06 |
| Popis: | Objective/Hypothesis The aim of this study was to assess the tissue response to Gore-Tex (expanded polytetrafluoroethylene) in rats and compare the results of surgical placement modalities. Study Design Prospective animal study. Materials and Methods Experiments were performed in 18 young Sprague-Dawley rats that were divided into 3 groups. Gore-Tex patches were implanted subcutaneously over the periosteum in the first group and under the periosteum in the other groups. Gore-Tex was immersed in an antibiotic-containing solution in the third group. All animals were killed 4 weeks after the procedure. The tissue samples were stained with hematoxylin and eosin stain and evaluated using a light microscope. Results The Gore-Tex patches were displaced and not observed at the originally implanted sites in the first group. The Gore-Tex patches were observed at the originally implanted sites in the other groups. In group 1, edema and inflammation were prominent. In the second group, ossification was detected in 5 rats and foreign-body reaction and edema were identified in 1 rat. In the third group, all of the rats were found to have developed ossification, but no inflammatory reactions were observed. Conclusions The results suggest that implanting synthetic graft materials immersed in an antibiotic solution at the subperiosteal plane provides better stabilization and low complication rates. |
| Databáze: | OpenAIRE |
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