A prospective and nationwide study investigating endophthalmitis following pars plana vitrectomy: incidence and risk factors
| Autor: | Somdutt Prasad, Balasubramanian Ramasamy, Roland Ling, Jonathan C Park, Stephen B. Shaw |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Pars plana
Male medicine.medical_specialty medicine.medical_treatment Eye Infections Infectious endophthalmitis Vitrectomy Cellular and Molecular Neuroscience Endophthalmitis Risk Factors Internal medicine Epidemiology Medicine Humans Prospective Studies Prospective cohort study business.industry Incidence (epidemiology) Incidence Middle Aged medicine.disease Sensory Systems United Kingdom Surgery Ophthalmology medicine.anatomical_structure Case-Control Studies Female Choroid business Sentinel Surveillance |
| Zdroj: | The British journal of ophthalmology. 98(4) |
| ISSN: | 1468-2079 |
| Popis: | This is the first nationwide prospective study to investigate the incidence and risk factors of endophthalmitis following pars plana vitrectomy (PPV).This was a prospective, nationwide case-control study. Cases of presumed infectious endophthalmitis within 6 weeks of PPV were reported via the established British Ophthalmological Surveillance Unit. The surveillance period was 2 years. Controls (patients who had PPV but no endophthalmitis) were recruited from nine randomly selected UK centres.37 reports were received and 28 cases met the diagnostic criteria for presumed infectious endophthalmitis following PPV. The incidence of endophthalmitis following PPV was 28 cases per 48 433 PPVs (1 in 1730 with a 95% CI of 1 in 1263 to 1 in 2747). 272 controls were randomly recruited from nine UK centres. Smaller gauge port sizes were not found to be a risk. Immunosuppression (OR 19.0, p=0.001) and preoperative topical steroids (OR 131.4, p0.001) increased the endophthalmitis risk. Operating for retinal detachment was associated with a reduced risk of endophthalmitis (OR 0.10, p=0.005).Endophthalmitis following PPV is rare. Operating with smaller gauge port sizes does not increase the risk of endophthalmitis. |
| Databáze: | OpenAIRE |
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