Practical considerations in the pharmacological treatment of postherpetic neuralgia for the primary care provider
| Autor: | Jamie S Massengill, John L Kittredge |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Polypharmacy
medicine.medical_specialty business.industry Postherpetic neuralgia Incidence (epidemiology) Alternative medicine herpes zoster Review medicine.disease clinical practice primary care Anesthesiology and Pain Medicine Quality of life (healthcare) practical guidelines pharmacological treatment Neuropathic pain medicine Physical therapy Intensive care medicine business Adverse effect Shingles postherpetic neuralgia |
| Zdroj: | Journal of Pain Research |
| ISSN: | 1178-7090 |
| Popis: | An estimated one million individuals in the US are diagnosed with herpes zoster (HZ; shingles) each year. Approximately 20% of these patients will develop postherpetic neuralgia (PHN), a complex HZ complication characterized by neuropathic pain isolated to the dermatome that was affected by the HZ virus. PHN is debilitating, altering physical function and quality of life, and commonly affects vulnerable populations, including the elderly and the immunocompromised. Despite the availability of an immunization for HZ prevention and several approved HZ treatments, the incidence of PHN is increasing. Furthermore, management of the neuropathic pain associated with PHN is often suboptimal, and the use of available therapeutics may be complicated by adverse effects and complex, burdensome treatment regimens, as well as by patients' comorbidities and polypharmacy, which may lead to drug-drug interactions. Informed and comprehensive assessments of currently available pharmacological treatment options to achieve effective pain control in the primary care setting are needed. In this article, we discuss the situation in clinical practice, review currently recommended prevention and treatment options for PHN, and outline practical considerations for the management of this neuropathic pain syndrome, with a focus on optimal, individual-based treatment plans for use in the primary care setting. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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