Interlaboratory Surveys of the Determination of Tumour Markers Scatter and Repeatability of the Results
| Autor: | G. Röhle, R. Kruse, W.-J. Geilenkeuser |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
endocrine system
Pathology medicine.medical_specialty Tissue Polypeptide Antigen Acid Phosphatase Clinical Biochemistry education Chorionic Gonadotropin Sensitivity and Specificity Human chorionic gonadotropin Carcinoembryonic antigen Antigen Biomarkers Tumor medicine Humans Antigens Tumor-Associated Carbohydrate biology business.industry Biochemistry (medical) Acid phosphatase Reproducibility of Results General Medicine Prostate-Specific Antigen Molecular biology Carcinoembryonic Antigen Prostate-specific antigen Prostatic acid phosphatase biology.protein Reagent Kits Diagnostic alpha-Fetoproteins Laboratories Peptides business Quantitative analysis (chemistry) |
| Popis: | Data collected between 1983 and 1991 in interlaboratory surveys of the determination of tumour markers are used to show the magnitude of the scatter of results from different laboratories for the analysis of a single quantity in a given matrix. These data also show that the varying specificity of different reagent combinations appears to make a considerable contribution to this scatter, and that the used reagent combinations were not of uniform quality over a relatively extended period. The results for the following tumour markers were studied: alpha-fetoprotein (AFP), carcinoembryonic antigen (CEA), human chorionic gonadotropin (hCG), human chorionic gonadotropin+beta-subunit (hCG+beta-hCG), tissue polypeptide antigen (TPA), carbohydrate antigen 19-9 (CA 19-9), cancer antigen 15-3 (CA 15-3), cancer antigen 125 (CA 125), prostatic acid phosphatase (PAP) and prostate-specific antigen (PSA). |
| Databáze: | OpenAIRE |
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