Epidemiologic and clinical characteristics of persons with serologic evidence of E. canis infection
| Autor: | J Kudlac, John R. Harkess, G L McKee, G R Istre, Barton W Rohrbach, S A Ewing |
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| Rok vydání: | 1990 |
| Předmět: |
Adult
Male Veterinary medicine medicine.medical_specialty Ehrlichia canis Rocky Mountain spotted fever Population Ehrlichia Rickettsiaceae Infections Serology Rickettsiaceae Internal medicine Epidemiology medicine Humans education Child education.field_of_study Leukopenia biology business.industry Public Health Environmental and Occupational Health Oklahoma Middle Aged biology.organism_classification medicine.disease Rash Antibodies Bacterial Canis Case-Control Studies Child Preschool Female medicine.symptom business Research Article |
| Zdroj: | American journal of public health. 80(4) |
| ISSN: | 0090-0036 |
| Popis: | The results of a serosurvey of Oklahomans for the presence of antibody to Ehrlichia canis is reported. Paired serum specimens, from patients lacking the serologic criteria for diagnosis of Rocky Mountain spotted fever (RMSF), were tested. A four-fold increase in E. canis-IFA antibody was found in 16/144 (11 percent) of these paired serum samples. Patients with serologic evidence of E. canis infection had a mean age of 34 years, 69 percent were male, and 63 percent lived in a town less than 10,000 population. Signs and symptoms included: fever 94 percent, headache 94 percent, fatigue 94 percent, anorexia 81 percent, nausea 60 percent, and rash 44 percent. When compared to control patients, whose sera were submitted for RMSF testing but did not meet serologic criteria for RMSF or E. canis, case-patients were more likely to have had leukopenia (OR = 4.9, 95 percent Cl = 1.2, 19.0) and tick exposure (OR = 9.5, 95 percent Cl = 1.4, 62.7). The results suggest E. canis, or a closely related agent, is a cause of human illness. Ticks are probable vector. |
| Databáze: | OpenAIRE |
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