Comparison of diffusion-weighted imaging and gadoxetic acid-enhanced MR images in the evaluation of hepatocellular carcinoma and hypovascular hepatocellular nodules

Autor: Paola Begini, Massimo Marignani, Gianfranco Delle Fave, Marco Di Pietropaolo, Elsa Iannicelli, Chiara Briani, Giulia Francesca Federici
Rok vydání: 2015
Předmět:
Gadolinium DTPA
Male
Gadoxetic acid
medicine.medical_specialty
Carcinoma
Hepatocellular
Hepatocellular carcinoma
Gadolinium
Contrast Media
chemistry.chemical_element
Nuclear Medicine and Imaging
medicine
Humans
Hypovascular nodules
Radiology
Nuclear Medicine and imaging
cardiovascular diseases
Aged
Retrospective Studies
Aged
80 and over
medicine.diagnostic_test
business.industry
Diffusion-weighted imaging
Gadoxetic acid-enhanced MRI
Gd-EOB-DTPA
Radiology
Nuclear Medicine and Imaging
Liver Neoplasms
Magnetic resonance imaging
Nodule (medicine)
Middle Aged
Image Enhancement
medicine.disease
Magnetic Resonance Imaging
digestive system diseases
Hyperintensity
Diffusion Magnetic Resonance Imaging
Liver
chemistry
Disease Progression
Female
Radiology
Mr images
medicine.symptom
Nuclear medicine
business
medicine.drug
Diffusion MRI
Zdroj: Clinical Imaging. 39:468-475
ISSN: 0899-7071
Popis: Purpose To compare diffusion-weighted imaging (DWI) and gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid (Gd-EOB-DTPA) magnetic resonance imaging (MRI) in the evaluation of hepatocellular carcinoma (HCC) and nodules at high risk of HCC transformation. Materials and methods We evaluated nodules' size, vascular pattern, and signal intensity on hepatobiliary phase images and on DWI of 105 nodules (41 cirrhotic patients). Results A total of 35/66 HCCs identified on Gd-EOB-DTPA MRI showed hyperintensity on DWI. A total of 25/39 nodules (hypovascular and hypointense nodule on hepatobiliary phase images) progressed to HCC (higher risk for nodules ≥10mm in size and hyperintense on DWI, P Conclusion Gd-EOB-DTPA MRI demonstrated a significant role in the identification of nodule at higher risk of HCC transformation, and hyperintensity on DWI was associated with progression to HCC.
Databáze: OpenAIRE
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